Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species.

Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species.
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DOI:
10.1007/s00251-012-0617-1
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发表时间:
2012-08
期刊:
影响因子:
3.2
通讯作者:
Bontrop, Ronald E.
Bontrop, Ronald E.
中科院分区:
医学4区
文献类型:
--
作者:
de Groot, Natasja G.;Otting, Nel;Robinson, James;Blancher, Antoine;Lafont, Bernard A. P.;Marsh, Steven G. E.;O'Connor, David H.;Shiina, Takashi;Walter, Lutz;Watkins, David I.;Bontrop, Ronald E.

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主要组织相容性复合体(MHC)在获得性免疫应答中起着核心作用。MHC区域的特征在于高基因密度,并且这些基因中的大多数显示出相当大的多态性。除了人类之外,非人类灵长类动物(NHP)的MHC也得到了很好的研究。本命名报告为科学界提供了最新的命名准则/规则和目前实施的巨猿,旧的和新的世界猴物种的命名修订。所有目前发表的不同巨猿、旧世界和新世界猴种属的MHC数据都存档在免疫多态性数据库(IPD)-MHC NHP数据库中。此外,IPD-MHC NHP数据库的管理员负责为新检测到的多态性提供官方名称。
The major histocompatibility complex (MHC) plays a central role in the adaptive immune response. The MHC region is characterised by a high gene density, and most of these genes display considerable polymorphism. Next to humans, non-human primates (NHP) are well studied for their MHC. The present nomenclature report provides the scientific community with the latest nomenclature guidelines/rules and current implemented nomenclature revisions for Great Ape, Old and New World monkey species. All the currently published MHC data for the different Great Ape, Old and New World monkey species are archived at the Immuno Polymorphism Database (IPD)-MHC NHP database. The curators of the IPD-MHC NHP database are, in addition, responsible for providing official designations for newly detected polymorphisms.
DOI: 10.1007/s002510050350
发表时间: 1998-02-01
期刊: IMMUNOGENETICS
影响因子: 3.2
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