Incidence of central serous chorioretinopathy (2011-2018): a nationwide population-based cohort study of Japan.
Incidence of central serous chorioretinopathy (2011-2018): a nationwide population-based cohort study of Japan.
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DOI：
10.1136/bjophthalmol-2021-319403
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发表时间：
2022-12
影响因子：
4.1
通讯作者：
Tsujikawa, Akitaka
中科院分区：
文献类型：
--
作者：
Kido, Ai;Miyake, Masahiro;Tamura, Hiroshi;Hiragi, Shusuke;Kimura, Takeshi;Ohtera, Shosuke;Takahashi, Ayako;Ooto, Sotaro;Kawakami, Koji;Kuroda, Tomohiro;Tsujikawa, Akitaka
本研究的目的是阐明中心性浆液性脉络膜视网膜病变(CSC)的流行病学背景，包括其发病率和治疗模式。这是一项基于人群的纵向队列研究，使用了日本厚生劳动省(MHLW)的全国医疗保险索赔数据库。由于日本采用全民健康保险，该数据库涵盖了日本95%以上的索赔。我们在得到MHLW的许可后访问了数据库中存储的所有数据。我们追踪了所有30岁或30岁以上的人，并确定了2011年1月至2018年12月期间新发的CSC患者。对每一年的CSC病例按年龄、性别进行分类，计算发病率。我们还确定了CSC的主要治疗方法，以阐明最初的治疗模式。8年间共发生 930例，男性占75.9%。30岁及以上人群的粗发病率(每10万 ，000人年)为34.0(95%CI 33.9~34.2)，男性为5 4.2(95%CI 5 3.9~5 4.4)，女性为15.7(95%CI 15.5~15.8)。男性的平均发病年龄低于女性(50.5±12.5岁对54.7±13.5岁)。大多数新诊断的CSC患者(86.8%)没有接受过主要治疗。本研究为阐明CSC的详细流行病学提供了全国性的基于人群的证据。这些结果将有助于进一步了解CSC的发病机制。
The aim of this study was to elucidate the epidemiological background of central serous chorioretinopathy (CSC), including its incidence and treatment pattern. This was a population-based longitudinal cohort study using a nationwide health insurance claims database of the Japan Ministry of Health, Labour and Welfare (MHLW). As Japan employs universal health coverage, the database covers more than 95% of claims issued in Japan. We accessed all data stored in the database with permission from the MHLW. We traced all individuals aged 30 years or older and identified individuals with new onset of CSC between January 2011 and December 2018. CSC cases were categorised by age and sex for each year, and incidence rate was calculated. We also identified major treatments for CSC to elucidate the initial treatment pattern. During the 8-year period, 247 930 incidences of CSC were identified, among which 75.9% were men. The crude incidence rate (per 100 000 person-years) in the general population aged 30 years or older was 34.0 (95% CI 33.9 to 34.2), in men was 54.2 (95% CI 53.9 to 54.4) and in women was 15.7 (95% CI 15.5 to 15.8). The mean age of onset was lower in men than in women (50.5±12.5 years vs 54.7±13.5 years). Most of the patients with newly diagnosed CSC (86.8%) did not receive major treatment. The current study provides the nationwide population-based evidence to clarify the detailed epidemiology of CSC. These results could help to understand the pathogenesis and mechanisms of CSC in the future.
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影响因子：
4.6
作者：
Miyake M;Ooto S;Yamashiro K;Takahashi A;Yoshikawa M;Akagi-Kurashige Y;Ueda-Arakawa N;Oishi A;Nakanishi H;Tamura H;Tsujikawa A;Yoshimura N
通讯作者：
Yoshimura N
影响因子：
2.9
作者：
Kido A;Tamura H;Ikeda HO;Miyake M;Hiragi S;Tsujikawa A
通讯作者：
Tsujikawa A
影响因子：
13.7
作者：
Mrejen, Sarah;Balaratnasingam, Chandrakumar;Yannuzzi, Lawrence A.
通讯作者：
Yannuzzi, Lawrence A.
影响因子：
6.3
作者：
KONO, S;IKEDA, M;OGATA, M
通讯作者：
OGATA, M
DOI：
10.1097/iae.0000000000001729
发表时间：
2018-07-01
影响因子：
3.3
作者：
Matet, Alexandre;Daruich, Alejandra;Behar-Cohen, Francine
通讯作者：
Behar-Cohen, Francine