Anticipating the course of an action: evidence from corticospinal excitability
Anticipating the course of an action: evidence from corticospinal excitability
复制标题
预测行动过程：来自皮质脊髓兴奋性的证据
作者：
Mattia Marangon;G. Bucchioni;Stefano Massacesi;U. Castiello
预期计划是一种对未来感知运动需求进行预测的能力，是灵活的、有目的的行为所必需的。一旦确定了行动目标，就可以选择实现该目标所需的运动细节。在这里，我们调查，如果预期的规划发生，即使在多步骤的行动正在进行。我们可能会问，参与运动选择的大脑回路是如何受到预期的目标中心任务需求的影响的？经颅磁刺激（TMS）被用来研究皮质脊髓兴奋性（CSE）的变化是如何依赖于预期的未来行动的预期任务变量。具体而言，单脉冲和成对脉冲TMS被用来评估皮质脊髓兴奋性在行动选择阶段准备把握execution.ResultsWe发现，在premovement阶段，有一个对象和肌肉的具体调制内在的手肌肉，将在即将到来的把握行动。根据参与者是否被指示执行单步或双步运动序列，皮质脊髓输出到适当的手部肌肉的调制取决于要抓住什么物体以及准备什么类型的运动。没有调制的兴奋性，观察在一步movement. ConclusionsExpectation的预期任务的需求起着重要的作用，在控制多步的行动，在此期间，正在进行的行为可能需要调整。这一发现支持的概念，涉及运动规划的皮质-皮质机制是特定的对象的属性以及运动序列的目标。
BackgroundAnticipatory planning, the ability to anticipate future perceptual-motor demands of a goal-oriented action sequence, is essential for flexible, purposeful behavior. Once an action goal has been defined, movement details necessary to achieve that goal can be selected. Here, we investigate if anticipatory planning takes place even when multi-step actions are being carried out. How, we may ask, are the cerebral circuits involved in movement selection influenced by anticipated object-center task demands? Transcranial magnetic stimulation (TMS) was used to investigate how changes in corticospinal excitability (CSE) are dependent on anticipated task variables of intended future actions. Specifically, single- and paired-pulse TMS was used to evaluate corticospinal excitability during the action selection phase preparatory to grasp execution.ResultsWe found that during the premovement phase, there is an object- and muscle-specific modulation in the intrinsic hand muscle that will be used during a forthcoming grasping action. Depending on whether the participants were instructed to perform a single- or double-step movement sequence, modulation of the corticospinal output to the appropriate hand muscles was dependent on what object was to be grasped and what type of movement was being prepared. No modulation in excitability was observed during one-step movements.ConclusionsAnticipation of intended task demands plays an important role in controlling multi- step actions during which ongoing behavior may need to be adjusted. This finding supports the notion that the cortico-cortical mechanism involving movement planning is specific for an object’s properties as well as for the goal of the movement sequence.
人类顶叶和前运动皮层中掌握表征的上下文敏感性的证据。
影响因子：
2.5
作者：
Marangon,Mattia;Jacobs,Stephane;Frey,ScottH
通讯作者：
Frey,ScottH
影响因子：
3.4
作者：
Fattori, P;Gamberini, M;Galletti, C
通讯作者：
Galletti, C