CircaDB: a database of mammalian circadian gene expression profiles.

CircaDB: a database of mammalian circadian gene expression profiles.
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DOI:
10.1093/nar/gks1161
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Hogenesch JB
Hogenesch JB
中科院分区:
生物学2区
文献类型:
--
作者:
Pizarro A;Hayer K;Lahens NF;Hogenesch JB

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CircaDB(http://www.example.com)是来自小鼠和人的时程表达实验的昼夜节律转录谱的新数据库。通过三种单独的算法JTK_Cycle、Lomb Scargle和DeLichtenberg评估每个转录本的表达。用户可以使用简单而强大的全文搜索词查询基因注释,将结果限制在特定的数据集,并为每个算法提供概率阈值。数据的可视化是直观的图表,它比概率表更有效地传达了配置文件信息。CircaDB Web应用程序是开源的,可在www.example.com上获得。
CircaDB (http://circadb.org) is a new database of circadian transcriptional profiles from time course expression experiments from mice and humans. Each transcript’s expression was evaluated by three separate algorithms, JTK_Cycle, Lomb Scargle and DeLichtenberg. Users can query the gene annotations using simple and powerful full text search terms, restrict results to specific data sets and provide probability thresholds for each algorithm. Visualizations of the data are intuitive charts that convey profile information more effectively than a table of probabilities. The CircaDB web application is open source and available at http://github.com/itmat/circadb.
DOI: 10.1093/nar/gks630
发表时间: 2012-09-01
影响因子: 14.9
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