Breast cancer screening and early diagnosis in Chinese women.
Breast cancer screening and early diagnosis in Chinese women.
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DOI：
10.20892/j.issn.2095-3941.2021.0676
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发表时间：
2022-04-05
影响因子：
5.5
通讯作者：
Shao, Zhi-Ming
中科院分区：
文献类型：
--
作者：
Ding, Rui;Xiao, Yi;Mo, Miao;Zheng, Ying;Jiang, Yi-Zhou;Shao, Zhi-Ming
乳腺癌是我国女性最常见的恶性肿瘤，其发病率呈上升趋势。定期筛查是早期发现肿瘤和改善患者预后的有效方法。本文就中国乳腺癌的流行病学变化及相关危险因素进行分析，并对建立适合中国妇女的乳腺癌筛查策略进行阐述。中国乳腺癌患者往往比西方患者更年轻，乳房更致密。因此，中国女性的初筛年龄应更早，并强调超声和钼靶联合筛查的重要性。此外，中国乳腺癌患者具有几个祖先特异性遗传特征，有助于确定识别高危人群的遗传筛查策略。在现有研究的基础上，我们总结了中国女性风险分层乳腺癌筛查指南的发展，并描述了中国乳腺癌患者预后的显著改善。
Breast cancer is the most common malignant tumor in Chinese women, and its incidence is increasing. Regular screening is an effective method for early tumor detection and improving patient prognosis. In this review, we analyze the epidemiological changes and risk factors associated with breast cancer in China and describe the establishment of a screening strategy suitable for Chinese women. Chinese patients with breast cancer tend to be younger than Western patients and to have denser breasts. Therefore, the age of initial screening in Chinese women should be earlier, and the importance of screening with a combination of ultrasound and mammography is stressed. Moreover, Chinese patients with breast cancers have several ancestry-specific genetic features, and aiding in the determination of genetic screening strategies for identifying high-risk populations. On the basis of current studies, we summarize the development of risk-stratified breast cancer screening guidelines for Chinese women and describe the significant improvement in the prognosis of patients with breast cancer in China.
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