A W-linked palindrome and gene conversion in New World sparrows and blackbirds.
A W-linked palindrome and gene conversion in New World sparrows and blackbirds.
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DOI：
10.1007/s10577-010-9134-y
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发表时间：
2010-07
影响因子：
2.6
通讯作者：
Thomas, James W.
中科院分区：
文献类型：
--
作者：
Davis, Jamie K.;Thomas, Pamela J.;Thomas, James W.
人类Y染色体男性特有区域的一个显著特征是存在大的、几乎相同的回文。这些回文通过回文臂之间的基因转换保持在接近相同的状态，并提出了中性和基于选择的理论来解释它们在人类Y和X染色体上的丰富。虽然这些提出的理论将适用于其他物种的性染色体，但几乎相同的回文是否是更广泛的分类群中性染色体的共同特征，包括其他四足动物，目前还没有确定。在这里，我们报道了一种新大陆麻雀，白喉麻雀(Zonotrichia Albiollis)的W染色体非重组部分的279kb区域的基因组测序和特征，以及Z染色体上的相应区域。与观察到的其他Y和W染色体一样，我们在白喉麻雀W染色体上检测到高重复元素含量(51%)和低基因含量。此外，我们在CHD1W基因5‘端两侧的W染色体上发现了一个22kb的近乎相同(>；99%)的回文。在这种回文的手臂之间很容易检测到基因转换的特征，就像在其他新大陆麻雀和黑鸟中出现的回文一样。因此，几乎相同的回文出现在鸟类的W染色体上，并可能由于人类性染色体上这些元素的丰富而产生的相同的力量而持续存在。
A hallmark feature of the male-specific region of the human Y chromosome is the presence of large and near-identical palindromes. These palindromes are maintained in a state of near identity via gene conversion between the arms of the palindrome, and both neutral and selection-based theories have been proposed to explain their enrichment on the human Y and X chromosomes. While those proposed theories would be applicable to sex chromosomes in other species, it has not been established whether near-identical palindromes are a common feature of sex chromosomes in a broader range of taxa, including other tetrapods. Here, we report the genomic sequencing and features of a 279-kb region of the non-recombining portion of the W chromosome spanning the CHD1W locus in a New World sparrow, the white-throated sparrow (Zonotrichia albicollis), and the corresponding region on the Z chromosome. As has been observed for other Y and W chromosomes, we detected a high repetitive element content (51%) and low gene content on the white-throated sparrow W chromosome. In addition, we identified a 22-kb near-identical (>99%) palindrome on the W chromosome that flanks the 5′ end of the CHD1W gene. Signatures of gene conversion were readily detected between the arms of this palindrome, as was the presence of this palindrome in other New World sparrows and blackbirds. Near-identical palindromes are therefore present on the avian W chromosome and may persist due to the same forces proposed for the enrichment of these elements on the human sex chromosomes.
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DOI：
10.1098/rstb.2000.0717
发表时间：
2000-11-29
影响因子：
6.3
作者：
Charlesworth, B;Charlesworth, D
通讯作者：
Charlesworth, D
影响因子：
30.8
作者：
LAKICH, D;KAZAZIAN, HH;GITSCHIER, J
通讯作者：
GITSCHIER, J
影响因子：
13.8
作者：
Jeanmougin, F;Thompson, JD;Gibson, TJ
通讯作者：
Gibson, TJ
果蝇米兰达（Drosophila Miranda）年轻Y染色体的基因组降解。
影响因子：
12.3
作者：
Bachtrog, Doris;Hom, Emily;Wong, Karen M.;Maside, Xulio;de Jong, Pieter
通讯作者：
de Jong, Pieter
影响因子：
2.6
作者：
Ezaz, Tariq;Moritz, Benjamin;Sarre, Stephen D.
通讯作者：
Sarre, Stephen D.