Equity in Genomics: A Brief Report on Cardiovascular Health Disparities in African American Adults.

Equity in Genomics: A Brief Report on Cardiovascular Health Disparities in African American Adults.
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DOI:
10.1097/jcn.0000000000000725
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发表时间:
2022-01-01
期刊:
The Journal of cardiovascular nursing
影响因子:
--
通讯作者:
Simmons LA
Simmons LA
中科院分区:
其他
文献类型:
--
作者:
Scott J;Cousin L;Woo J;Gonzalez-Guarda R;Simmons LA

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非裔美国人比美国所有其他人群更有可能死于心血管疾病(CVD)虽然技术进步支持了应用遗传学/基因组学来解决CVD的快速增长,但大多数研究都是在欧洲裔美国人中进行的。基因组样本中缺乏非洲裔美国人的代表性限制了公平应用精准医学工具的进展,如果不加以补救,这将扩大心血管疾病的差异。本报告总结了遗传/基因组学的进展,这些进展为精确健康提供了信息,并对非裔美国成年人的CV差异产生了影响。我们为护士科学家提供建议,帮助他们成为开发精确健康工具的领导者,以促进人口健康公平。基因组学将继续推动CVD预防和管理的进步,公平的进步势在必行。护理应该利用公众的信任及其在临床和社区环境中的广泛存在,以防止非洲裔美国人之间心血管疾病差异的恶化。
African Americans are more likely to die from cardiovascular disease (CVD) than all other populations in the U.S. Although technological advances have supported rapid growth in applying genetics/genomics to address CVD, most research has been conducted among European Americans. The lack of African American representation in genomic samples has limited progress in equitably applying precision medicine tools, which will widen CVD disparities if not remedied. This report summarizes the genetic/genomic advances that inform precision health and the implications for CV disparities in African American adults. We provide nurse scientists recommendations for becoming leaders in developing precision health tools that promote population health equity. Genomics will continue to drive advances in CVD prevention and management, and equitable progress is imperative. Nursing should leverage the public’s trust and its widespread presence in clinical and community settings to prevent the worsening of CVD disparities among African-Americans.
DOI: 10.1371/journal.pone.0090255
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Ni X;Zhang J
通讯作者: Zhang J