Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases.

Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases.
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DOI:
10.4046/trd.2020.0088
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发表时间:
2021-01
影响因子:
2.9
通讯作者:
Khanna A
Khanna A
中科院分区:
其他
文献类型:
--
作者:
Deshmukh K;Khanna A

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在全球范围内,心血管疾病和慢性阻塞性肺疾病(COPD)是非传染性疾病负担的主要原因。呼吸困难和疲劳等重叠症状,加上医生对COPD缺乏认识,是诊断不足和导致与COPD相关的次优护理的关键原因。过去已经发表了很多关于COPD心血管合并症的发病机制和影响的文章。然而,缺乏对COPD管理在常见心脏病中的患病率和影响的全面综述。本研究的目的是总结目前关于COPD在心力衰竭、缺血性心脏病和房颤中的患病率的知识。我们还讨论了现实生活中的临床表现和管理慢性阻塞性肺疾病的实际意义。我们在PubMed、Scopus、EMBASE和Google Scholar中检索了1981年至2020年5月发表的报告COPD在三种特定心脏疾病中患病率的研究。COPD在心力衰竭、房颤和缺血性心脏病中的患病率较高。尽管如此,在大多数心脏病患者中,COPD仍然诊断不足和管理不足。心脏病中COPD诊断的临床意义包括识别过度充气(一种可治疗的特征),实施COPD急性加重(AECOPD)预防策略,以及降低过度使用利尿剂的风险。用于管理COPD的药理学药物已显示出对心脏功能和死亡率的有益作用。COPD的适当管理通过减少过度充气和预防AECOPD来改善心血管结局,从而降低死亡风险,改善运动耐量和生活质量。
Globally, cardiovascular diseases and chronic obstructive pulmonary disease (COPD) are the leading causes of the noncommunicable disease burden. Overlapping symptoms such as breathing difficulty and fatigue, with a lack of awareness about COPD among physicians, are key reasons for under-diagnosis and resulting sub-optimal care relative to COPD. Much has been published in the past on the pathogenesis and implications of cardiovascular comorbidities in COPD. However, a comprehensive review of the prevalence and impact of COPD management in commonly encountered cardiac diseases is lacking. The purpose of this study was to summarize the current knowledge regarding the prevalence of COPD in heart failure, ischemic heart disease, and atrial fibrillation. We also discuss the real-life clinical presentation and practical implications of managing COPD in cardiac diseases. We searched PubMed, Scopus, EMBASE, and Google Scholar for studies published 1981–May 2020 reporting the prevalence of COPD in the three specified cardiac diseases. COPD has high prevalence in heart failure, atrial fibrillation, and ischemic heart disease. Despite this, COPD remains under-diagnosed and under-managed in the majority of patients with cardiac diseases. The clinical implications of the diagnosis of COPD in cardiac disease includes the recognition of hyperinflation (a treatable trait), implementation of acute exacerbations of COPD (AECOPD) prevention strategies, and reducing the risk of overuse of diuretics. The pharmacological agents for the management of COPD have shown a beneficial effect on cardiac functions and mortality. The appropriate management of COPD improves the cardiovascular outcomes by reducing hyperinflation and preventing AECOPD, thus reducing the risk of mortality, improving exercise tolerance, and quality of life.
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