All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study.
All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study.
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DOI：
10.1136/bmjopen-2021-057369
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发表时间：
2023-03-01
期刊：
影响因子：
2.9
通讯作者：
Lakoh, Sulaiman
中科院分区：
文献类型：
--
作者：
Farrant, Olivia;Baldeh, Mamadu;Kamara, Joseph Baio;Bailey, Emma;Sevalie, Stephen;Deen, Gibrilla;Russell, James Baligeh Walter;Youkee, Daniel;Leather, Andy J. M.;Davies, Justine;Lakoh, Sulaiman
研究塞拉利昂COVID-19患者的死亡率，探索COVID-19大流行期间与死亡率相关的因素，并强调在脆弱的卫生系统中治疗新型流行病患者的复杂性。前瞻性单中心队列研究。从纸质病历中提取数据并转移到电子数据库中。使用Stata V.17中的描述性统计，比较了幸存者和非幸存者之间的具体指标。塞拉利昂弗里敦康诺特医院传染病科（IDU）参与者均为2020年3月至7月期间入住IDU的患者。该研究的主要结局是检查塞拉利昂疑似COVID-19住院患者的全因死亡率，次要结局指标是检查与COVID-19阳性患者死亡率相关的因素。261名参与者被纳入研究。总体而言，41.3%的注射吸毒者死亡，而大流行前的住院死亡率为23.8%。导致死亡率较高的因素是COVID-19感染（aOR 5. 61，95% CI 1. 19至26. 30，p= 0. 02）和高血压（aOR 9. 30，95% CI 1. 18至73. 27，p= 0. 03）。它提供了一个深入了解在一个脆弱的卫生系统的流行病期间提供一线医疗保健的现实。
To study the mortality of patients with COVID-19 in Sierra Leone, to explore the factors associated with mortality during the COVID-19 pandemic and to highlight the complexities of treating patients with a novel epidemic disease in a fragile health system. A prospective single-centre cohort study. Data were extracted from paper medical records and transferred onto an electronic database. Specific indicators were compared between survivors and non-survivors, using descriptive statistics in Stata V.17. The infectious diseases unit (IDU) at Connaught Hospital in Freetown, Sierra Leone Participants were all patients admitted to the IDU between March and July 2020. The primary outcome of the study was to examine the all-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone and the secondary outcome measures were to examine factors associated with mortality in patients positive for COVID-19. 261 participants were included in the study. Overall, 41.3% of those admitted to the IDU died, compared with prepandemic in-hospital mortality of 23.8%. Factors contributing to the higher mortality were COVID-19 infection (aOR 5.61, 95% CI 1.19 to 26.30, p=0.02) and hypertension (aOR 9.30, 95% CI 1.18 to 73.27, p=0.03) This study explores the multiple factors underpinning a doubling in facility mortality rate during the COVID-19 pandemic in Sierra Leone. It provides an insight into the realities of providing front-line healthcare during a pandemic in a fragile health system.
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影响因子：
8.1
作者：
Barrie MB;Lakoh S;Kelly JD;Kanu JS;Squire JS;Koroma Z;Bah S;Sankoh O;Brima A;Ansumana R;Goldberg SA;Chitre S;Osuagwu C;Frankfurter R;Maeda J;Barekye B;Numbere TW;Abdulaziz M;Mounts A;Blanton C;Singh T;Samai M;Vandi M;Richardson ET
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影响因子：
3.7
作者：
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通讯作者：
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影响因子：
4.4
作者：
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DOI：
10.1001/jama.2020.6775
发表时间：
2020-01-01
期刊：
JAMA, Journal of the American Medical Association
影响因子：
--
作者：
Richardson, Safiya;Hirsch, Jamie S.;,
通讯作者：
,
影响因子：
3.7
作者：
Kassa, Getachew;Dougherty, Gillian;Rabkin, Miriam
通讯作者：
Rabkin, Miriam