Mechanisms of gamma oscillations.
Mechanisms of gamma oscillations.
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DOI：
10.1146/annurev-neuro-062111-150444
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发表时间：
2012
影响因子：
13.9
通讯作者：
Wang XJ
中科院分区：
文献类型：
--
作者：
Buzsáki G;Wang XJ
在清醒和睡眠状态下，伽马节律在大脑的许多区域都可以观察到，但其功能和机制仍然存在争议。在这里，我们回顾了伽马振荡背后的细胞和突触机制，并概述了经验问题和有争议的概念问题。我们的主要观点如下：第一，伽马频段节律的产生与周围性抑制密不可分。其次，伽马振荡是短暂的，通常出现在激发和抑制的协同作用中，这可以被检测到为局部场势。第三，伽马节律通常与单个神经元的不规则放电一致，伽马振荡的网络频率根据潜在机制的不同而有很大差异。为了记录伽马振荡，应努力将它们与仅仅是伽马频段功率的增加和/或尖峰活动的增加区分开来。第四，伽马振荡的大小受到较慢节奏的调制。这种交叉频率耦合可用于耦合皮质回路的有源斑块。伽马振荡由于其无处不在的性质以及与局部电路的“工作模式”的强烈相关性，继续为健康和疾病中的神经元种群动力学提供重要线索。
Gamma rhythms are commonly observed in many brain regions during both waking and sleep states, yet their functions and mechanisms remain a matter of debate. Here we review the cellular and synaptic mechanisms underlying gamma oscillations and outline empirical questions and controversial conceptual issues. Our main points are as follows: First, gamma-band rhythmogenesis is inextricably tied to perisomatic inhibition. Second, gamma oscillations are short-lived and typically emerge from the coordinated interaction of excitation and inhibition, which can be detected as local field potentials. Third, gamma rhythm typically concurs with irregular firing of single neurons, and the network frequency of gamma oscillations varies extensively depending on the underlying mechanism. To document gamma oscillations, efforts should be made to distinguish them from mere increases of gamma-band power and/or increased spiking activity. Fourth, the magnitude of gamma oscillation is modulated by slower rhythms. Such cross-frequency coupling may serve to couple active patches of cortical circuits. Because of their ubiquitous nature and strong correlation with the “operational modes” of local circuits, gamma oscillations continue to provide important clues about neuronal population dynamics in health and disease.
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DOI：
10.1073/pnas.1011284108
发表时间：
2011-07-05
影响因子：
11.1
作者：
Buffalo, Elizabeth A.;Fries, Pascal;Desimone, Robert
通讯作者：
Desimone, Robert
影响因子：
--
作者：
Berger, H
通讯作者：
Berger, H
影响因子：
5.5
作者：
Adrian, ED
通讯作者：
Adrian, ED
DOI：
10.1016/0013-4694(80)90319-3
发表时间：
1980-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
BRESSLER, SL;FREEMAN, WJ
通讯作者：
FREEMAN, WJ
影响因子：
2.9
作者：
Börgers, C;Kopell, N
通讯作者：
Kopell, N