Nanoparticle-based imaging of inflammatory bowel disease.
Nanoparticle-based imaging of inflammatory bowel disease.
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基于纳米粒子的炎症性肠病成像。
DOI：
10.1002/wnan.1357
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发表时间：
2016-03
期刊：
影响因子：
--
通讯作者：
Tao, Xiaofeng
中科院分区：
文献类型：
--
作者：
Wu, Yingwei;Briley, Karen;Tao, Xiaofeng
虽然炎症性肠病（IBD）已被广泛研究，但其发病机制仍不完全清楚。因此，治疗选择仍然不令人满意和非特异性。随着影像学诊断技术的快速发展，计算机断层扫描（CT）和磁共振成像（MRI）等成像方式在IBD诊断和评估中发挥着越来越重要的作用。纳米技术的最新发展利用跨学科方法来特异性靶向分子或细胞IBD病理过程，从而产生具有高特异性和诊断和/或治疗功效的纳米颗粒（NP）。基于纳米的成像，其结合了纳米技术和成像模式，可以允许IBD的早期检测，疾病活动的监测，并且可以用于在细胞和/或分子水平上监测治疗反应。本文就纳米成像技术及其在IBD领域的应用作一综述。
Although inflammatory bowel disease (IBD) has been extensively studied, the pathogenesis is still not completely understood. As a result, the treatment options remain unsatisfactory and nonspecific. With the rapid advancement of diagnostic imaging techniques, imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) are playing a more important role in IBD diagnosis and evaluation. Recent developments in nanotechnology utilize an interdisciplinary approach to specifically target molecular or cellular IBD pathological process thereby generating nanoparticles (NPs) with high specificity and diagnostic and/or therapeutic efficacy. Nano-based imaging, which incorporates nanotechnology and imaging modalities, may allow for the early detection of IBD, the monitoring of disease activity, and may be used to monitor the therapeutic response at cellular and/or molecular level. In this review, we highlight issues related to nano-based imaging and its application in IBD field.
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影响因子：
4.3
作者：
Jong‐Min Park;Na-Young Han;Youngmin Han;M. Chung;H. Lee;K. Ko;Eun-Hee Kim;K. Hahm
通讯作者：
Jong‐Min Park;Na-Young Han;Youngmin Han;M. Chung;H. Lee;K. Ko;Eun-Hee Kim;K. Hahm
影响因子：
3.5
作者：
Xiaoyan Lu;C. Ji;Tingting Jin;Xiaohui Fan
通讯作者：
Xiaoyan Lu;C. Ji;Tingting Jin;Xiaohui Fan
影响因子：
24
作者：
Briley-Saebo, Karen C.;Tuyen Hoang Nguyen;Saeboe, Alexander M.;Cho, Young-Seok;Ryu, Sung Kee;Volkava, Eugenia;Dickson, Stephen;Leibundgut, Gregor;Weisner, Philipp;Green, Simone;Casanada, Florence;Miller, Yury I.;Shaw, Walter;Witztum, Joseph L.;Fayad, Zahi A.;Tsimikas, Sotirios
通讯作者：
Tsimikas, Sotirios
DOI：
10.3109/00365529009093157
发表时间：
1990
期刊：
Scandinavian journal of gastroenterology. Supplement
影响因子：
--
作者：
G. Crama-bohbouth;A. Peña;J. Arndt;R. T. Tjon;A. Tham;H. Verspaget;I. Weterman;E. Pauwels;C. Lamers
通讯作者：
G. Crama-bohbouth;A. Peña;J. Arndt;R. T. Tjon;A. Tham;H. Verspaget;I. Weterman;E. Pauwels;C. Lamers
DOI：
10.1016/j.bpg.2014.04.010
发表时间：
2014-06-01
影响因子：
3.2
作者：
Dambha, F.;Carroll, N.
通讯作者：
Carroll, N.