Neural reorganization following sensory loss: the opportunity of change.

Neural reorganization following sensory loss: the opportunity of change.
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DOI:
10.1038/nrn2758
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发表时间:
2010-01
影响因子:
34.7
通讯作者:
Pascual-Leone, Alvaro
Pascual-Leone, Alvaro
中科院分区:
医学1区
文献类型:
--
作者:
Merabet, Lotfi B.;Pascual-Leone, Alvaro

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Growing evidence suggests that sensory deprivation is associated with dramatic crossmodal neuroplastic changes in the brain. In the case of visual and auditory deprivation, there is functional recruitment of brain areas normally associated with the sense that is lost by those sensory modalities that are spared. Furthermore, these changes seem to underlie adaptive and compensatory behaviours observed in both blind and deaf individuals. Although there are differences between these two populations due the very nature of the deprived sensory modality, there seem to be common principles regarding how the brain copes with sensory loss and the factors that influence how neuroplastic changes come about. Here, we discuss crossmodal neuroplasticity with regards to behavioural adaptation following sensory deprivation and highlight the possibility of maladaptive consequences within the context of rehabilitation.
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