Hypertriglyceridemia and atherosclerosis.

Hypertriglyceridemia and atherosclerosis.
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高甘油三酯血症和动脉粥样硬化

DOI:
10.1186/s12944-017-0625-0
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发表时间:
2017-12-06
影响因子:
4.5
通讯作者:
Li X
Li X
中科院分区:
医学3区
文献类型:
--
作者:
Peng J;Luo F;Ruan G;Peng R;Li X

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动脉粥样硬化性心血管疾病(ASCVD)是主要的死亡原因,低密度脂蛋白胆固醇(LDL-C)升高已被证实是动脉粥样硬化的独立危险因素。最近,越来越多的证据表明,高甘油三酯血症与增加的ASCVD风险有关。但甘油三酯(TG)致动脉粥样硬化的机制尚不清楚。因此,本文就高甘油三酯血症相关的临床研究及致动脉粥样硬化机制进行综述,以期为ASCVD的防治提供参考。
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk. But the proatherogenic mechanism of triglyceride (TG) remains unclear. Therefore, this article focuses on the clinical studies and proatherogenic mechanism related to hypertriglyceridemia, in order to provide reference for the prevention and treatment of ASCVD.
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