Maternal vitamin D status, prolonged labor, cesarean delivery and instrumental delivery in an era with a low cesarean rate.

Maternal vitamin D status, prolonged labor, cesarean delivery and instrumental delivery in an era with a low cesarean rate.
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DOI:
10.1038/jp.2014.139
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发表时间:
2015-01
影响因子:
2.9
通讯作者:
Bodnar, L. M.
Bodnar, L. M.
中科院分区:
医学3区
文献类型:
--
作者:
Gernand, A. D.;Klebanoff, M. A.;Simhan, H. N.;Bodnar, L. M.

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To examine the association between maternal 25-hydroxyvitamin D (25(OH)D) and adverse labor and delivery outcomes. We measured serum 25(OH)D at ≤26 weeks gestation in a random subsample of vertex, singleton pregnancies in women who labored (n=2798) from the 12 site Collaborative Perinatal Project (1959–66). We used labor and delivery data to classify cases of adverse outcomes. Twenty-four percent of women were vitamin D deficient (25(OH)D <30 nmol/L) and 4.5%, 3.3%, 1.9%, and 7.5% of women had prolonged stage 1 labor, prolonged stage 2 labor, primary cesarean delivery, or indicated instrumental delivery, respectively. After adjustment for prepregnancy BMI, race, and study site, 25(OH)D concentrations were not associated with risk of prolonged stage 1 or 2, cesarean delivery, or instrumental delivery. Maternal vitamin D status at ≤26 weeks was not associated with risk of prolonged labor or operative delivery in an era with a low cesarean rate.
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