The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion.
The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion.
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Rab7效应子WDR91通过调节溶酶体融合促进神经元自噬-溶酶体降解
DOI:
10.1083/jcb.202007061
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发表时间:
2021-08-02
期刊:
影响因子:
--
通讯作者:
Yang C
中科院分区:
文献类型:
--
作者:
Xing R;Zhou H;Jian Y;Li L;Wang M;Liu N;Yin Q;Liang Z;Guo W;Yang C
How distinct Rab7 effectors coordinate to regulate lysosomal homeostasis is largely unknown. Xing et al. reveal that the Rab7 effector WDR91 competes with VPS41, another Rab7 effector, to maintain appropriate lysosomal fusion required for autophagy-lysosome degradation in neurons.
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DOI:
10.1073/pnas.1307074110
发表时间:
2013-08-13
影响因子:
11.1
作者:
Graham, Stephen C.;Wartosch, Lena;Owen, David J.
通讯作者:
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DOI:
10.1083/jcb.201506081
发表时间:
2016-01-18
期刊:
The Journal of cell biology
影响因子:
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通讯作者:
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10.1083/jcb.108.3.855
发表时间:
1989-03
期刊:
The Journal of cell biology
影响因子:
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通讯作者:
Heuser J
DOI:
10.1083/jcb.148.6.1231
发表时间:
2000-03-20
期刊:
The Journal of cell biology
影响因子:
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作者:
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通讯作者:
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影响因子:
4
作者:
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通讯作者:
Ungermann, Christian