Neuron/target plasticity in the peripheral gustatory system.
Neuron/target plasticity in the peripheral gustatory system.
复制标题
外周味觉系统中的神经元/目标可塑性。
DOI：
10.1002/cne.11017
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Hill,DavidL
中科院分区：
文献类型：
--
作者：
Shuler,MarshallG;Krimm,RobinF;Hill,DavidL
Taste bud volume on the anterior tongue in adult rats is matched by an appropriate number of innervating geniculate ganglion cells. The larger the taste bud, the more geniculate ganglion cells that innervate it. To determine if such a match is perturbed in the regenerated gustatory system under different dietary conditions, taste bud volumes and numbers of innervating neurons were quantified in adult rats after unilateral axotomy of the chorda tympani nerve and/or maintenance on a sodium‐restricted diet. The relationship between taste bud size and innervation was eliminated in rats merely fed a sodium‐restricted diet; individual taste bud volumes were smaller than predicted by the corresponding number of innervating neurons. Surprisingly, the relationship was disrupted in a similar way on the intact side of the tongue in unilaterally sectioned rats, with no diet‐related differences. The mismatch in these groups was due to a decrease in average taste bud volumes and not to a change in numbers of innervating ganglion cells. In contrast, individual taste bud volumes were larger than predicted by the corresponding number of innervating neurons on the regenerated side of the tongue; again, with no diet‐related differences. However, the primary variable responsible for disrupting the function on the regenerated side was an approximate 20% decrease in geniculate ganglion cells available to innervate taste buds. Therefore, the neuron/target match in the peripheral gustatory system is susceptible to surgical and/or dietary manipulations that act through multiple mechanisms. This system is ideally suited to model sensory plasticity in adults. J. Comp. Neurol. 472:183–192, 2004. © 2004 Wiley‐Liss, Inc.
登录
查看更多内容
聚（dA-dC）.聚（dC-bT）的Z型形式？
DOI：
--
发表时间：
1982
期刊：
影响因子：
--
作者：
M. Vorlíčková;J. Kypr;Š. Štokrová;J. Šponar
通讯作者：
J. Šponar
原子分辨率的 RNA 双螺旋片段。
影响因子：
5.6
作者：
J. Rosenberg;N. Seeman;R. O. Day;Alexander Rich
通讯作者：
Alexander Rich
A-、B- 和 Z-DNA 的解剖结构。
影响因子：
56.9
作者：
R. Dickerson;H. Drew;B. N. Conner;R. M. Wing;A. Fratini;M. Kopka
通讯作者：
M. Kopka
含有交替硫代磷酸酯键的 d(GC) 和 d(CG) 八聚体的合成：硫代磷酸酯基团对 B-Z 转变的影响。
影响因子：
2.9
作者：
R. Cosstick;F. Eckstein
通讯作者：
F. Eckstein
脱氧腺苷基-3-甲基膦酸酯-5-胸苷二水合物 (d-ApT x 2H2O) 的分子结构，是一种具有中性磷酸二酯骨架的二核苷单磷酸盐。
影响因子：
14.9
作者：
K. K. Chacko;K. Lindner;W. Saenger;P. Miller
通讯作者：
P. Miller