Recombination and the progression of meiosis in Saccharomyces cerevisiae.
Recombination and the progression of meiosis in Saccharomyces cerevisiae.
复制标题
酿酒酵母的重组和减数分裂的进展。
DOI:
10.1093/genetics/146.2.481
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发表时间:
1997
期刊:
影响因子:
3.3
通讯作者:
Malone,RE
中科院分区:
文献类型:
--
作者:
Galbraith,AM;Bullard,SA;Jiao,K;Nau,JJ;Malone,RE
Recombination is an essential part of meiosis; in almost all organisms, includingSaccharomyces cerevisiae,proper chromosome segregation and the viability of meiotic products is dependent upon normal levels of recombination. In this article we examine the kinetics of the meiotic divisions in four mutants defective in the initiation of recombination. We find that mutations in any of three Early Exchange genes (REC104, REC114orREC102) confer a phenotype in which the reductional division occurs earlier than in an isogenic wild-type diploid. We also present data confirming previous reports that strains with a mutation in the Early Exchange geneMEI4undergo the first division at about the same time as wild-type cells. Therec104mutation is epistatic to themei4mutation for the timing of the first division. These observations suggest a possible relationship between the initiation of recombination and the timing of the reductional division. These data also allow these four Early Exchange genes examined to be distinguished in terms of their role in coordinating recombination with the reductional division.
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影响因子:
3.3
作者:
Mao-Draayer,Y;Galbraith,AM;Pittman,DL;Cool,M;Malone,RE
通讯作者:
Malone,RE
影响因子:
3.3
作者:
Nag,DK;Scherthan,H;Rockmill,B;Bhargava,J;Roeder,GS
通讯作者:
Roeder,GS
影响因子:
3.3
作者:
Elizabeth Orvis Shuster;Breck Byers
通讯作者:
Breck Byers
影响因子:
3.3
作者:
Weber,L;Byers,B
通讯作者:
Byers,B
影响因子:
3.3
作者:
S. Klapholz;C. Waddell;R. E. Esposito
通讯作者:
S. Klapholz;C. Waddell;R. E. Esposito