Current trends in high throughput proteomics in cyanobacteria

Current trends in high throughput proteomics in cyanobacteria
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蓝藻高通量蛋白质组学的当前趋势

DOI:
10.1016/j.febslet.2009.03.062
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发表时间:
2009
期刊:
影响因子:
3.5
通讯作者:
P. Wright
P. Wright
中科院分区:
生物学3区
文献类型:
--
作者:
S. Ow;P. Wright

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在基因组测序和蓝藻菌株的高通量蛋白质组学方面的进展导致了来自少数实验室的13份发表的报告。这些成功的研究集中在聚球藻、发菜和鱼腥藻菌株、原氯球菌和耐盐真卤藻上。在这些大规模研究中开发和应用的新的量化方面的含义是在高级蓝藻研究之后进行评估的。此外,蓝藻蛋白质组学的传统高通量分析和早期高通量分析的贡献被比较和总结。最后,提出了将趋势和未来挑战联系起来的意见。该综述旨在推动蛋白质组学与蓝藻研究之间的协同作用,以提高其技术和生物学意义。
Advancements in genome sequencing and high throughput proteomics of cyanobacterial strains led to 13 published reports, from a small number of laboratories. These successful studies focused on Synechocystis, Nostoc and Anabaena strains, prochlorococcus, and halotolerant Euhalothece. The implications of emerging quantitative aspects developed and applied in these large-scale studies are assessed in the wake of advanced cyanobacterial research. Furthermore, contributions from traditional and early high throughput analysis of cyanobacterial proteomics are compared and summarised. Finally, opinions are provided to link both the trends and the future challenges. This review aims to push the synergy between proteomics and cyanobacterial research to improve both the technical and biological significance.
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