Respiratory supercomplexes: plasticity and implications.

Respiratory supercomplexes: plasticity and implications.
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DOI:
10.2741/4327
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发表时间:
2015-01-01
期刊:
Frontiers in bioscience (Landmark edition)
影响因子:
--
通讯作者:
Bai Y
Bai Y
中科院分区:
其他
文献类型:
--
作者:
Porras CA;Bai Y

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The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging.
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