Genetic analysis of the cap5 locus of Staphylococcus aureus.
Genetic analysis of the cap5 locus of Staphylococcus aureus.
复制标题
金黄色葡萄球菌 cap5 位点的遗传分析。
DOI：
10.1111/j.1574-6968.1999.tb13360.x
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发表时间：
1999
影响因子：
2.1
通讯作者：
Timothy J. Foster
中科院分区：
文献类型：
--
作者：
E. Wann;B. Dassy;Jean;Timothy J. Foster
金黄色葡萄球菌表达至少八种不同的荚膜多糖（CP）血清型。参与血清型1、5和8表达的基因簇已被克隆和测序。在这份报告中，我们描述了血清型5荚膜多糖缺陷突变体的分离和分析。通过遗传互补将实验室菌株8325-4和RN 4220中自然发生的cap突变定位到cap 5E基因上。cap 5 H-K基因通过转导和互补作用与CP 5血清型特异性有关。
Staphylococcus aureus expresses at least eight distinct serotypes of capsular polysaccharide (CP). Gene clusters involved in the expression of serotypes 1, 5 and 8 have been cloned and sequenced. In this report we describe the isolation and analysis of serotype 5 capsular polysaccharide-defective mutants. A naturally occurring cap mutation in the laboratory strains 8325-4 and RN4220 was mapped to the cap5E gene by genetic complementation. The cap5H-K genes were shown to be responsible for CP5 serotype specificity by transduction and complementation.
DOI：
10.1099/00221287-143-7-2395
发表时间：
1997-07-01
期刊：
MICROBIOLOGY-UK
影响因子：
--
作者：
Sau, S;Bhasin, N;Lee, CY
通讯作者：
Lee, CY