Fatty acid oxidation: driver of lymph node metastasis.
Fatty acid oxidation: driver of lymph node metastasis.
复制标题
脂肪酸氧化:淋巴结转移的驱动因素。
DOI:
10.1186/s12935-021-02057-w
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发表时间:
2021-07-03
影响因子:
5.8
通讯作者:
Tang YL
中科院分区:
文献类型:
--
作者:
Li M;Xian HC;Tang YJ;Liang XH;Tang YL
Fatty acid oxidation (FAO) is the emerging hallmark of cancer metabolism because certain tumor cells preferentially utilize fatty acids for energy. Lymph node metastasis, the most common way of tumor metastasis, is much indispensable for grasping tumor progression, formulating therapy measure and evaluating tumor prognosis. There is a plethora of studies showing different ways how tumor cells metastasize to the lymph nodes, but the role of FAO in lymph node metastasis remains largely unknown. Here, we summarize recent findings and update the current understanding that FAO may enable lymph node metastasis formation. Afterward, it will open innovative possibilities to present a distinct therapy of targeting FAO, the metabolic rewiring of cancer to terminal cancer patients.
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影响因子:
16.6
作者:
Chen C;He W;Huang J;Wang B;Li H;Cai Q;Su F;Bi J;Liu H;Zhang B;Jiang N;Zhong G;Zhao Y;Dong W;Lin T
通讯作者:
Lin T
影响因子:
64.5
作者:
Chang CH;Curtis JD;Maggi LB Jr;Faubert B;Villarino AV;O'Sullivan D;Huang SC;van der Windt GJ;Blagih J;Qiu J;Weber JD;Pearce EJ;Jones RG;Pearce EL
通讯作者:
Pearce EL
影响因子:
29
作者:
Divakaruni AS;Hsieh WY;Minarrieta L;Duong TN;Kim KKO;Desousa BR;Andreyev AY;Bowman CE;Caradonna K;Dranka BP;Ferrick DA;Liesa M;Stiles L;Rogers GW;Braas D;Ciaraldi TP;Wolfgang MJ;Sparwasser T;Berod L;Bensinger SJ;Murphy AN
通讯作者:
Murphy AN
影响因子:
20.3
作者:
Hirakawa, Satoshi;Brown, Lawrence F.;Detmar, Michael
通讯作者:
Detmar, Michael
影响因子:
4.2
作者:
Hinnebusch, BF;Meng, SF;Hodin, RA
通讯作者:
Hodin, RA