Primary Progressive Apraxia of Speech: From Recognition to Diagnosis and Care.
Primary Progressive Apraxia of Speech: From Recognition to Diagnosis and Care.
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DOI：
10.1080/02687038.2020.1787732
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发表时间：
2021
期刊：
影响因子：
2
通讯作者：
Josephs KA
中科院分区：
文献类型：
--
作者：
Duffy JR;Utianski RL;Josephs KA
言语失用症（AOS）可以由神经退行性疾病引起，并且有时是其表现体征（即，原发性进行性言语失用症（PPAOS）。在过去的几十年里，我们对PPAOS的认识已经从临床认识发展到对其核心和相关临床特征、其与原发性进行性失语的区别和关系、其时间进程和最终进展包括其他神经功能缺损以及其神经影像学相关性和潜在病理学的更全面理解。本文提供了一个全面的文献总结，建立了目前的知识基础PPAOS和进行性AOS，因为它与进行性失语症共同发生。它回顾了它作为一种公认的综合征出现的历史;它与原发性进行性失语症的语法不清/不流利变体的关系;它的显著感知特征和亚型;声学和结构/生理成像指标，其存在，严重程度和失语症的区别;以及有关其管理和护理的原则和可用数据。AOS是神经退行性疾病的一种表现形式。原发性进行性言语失用症是一种可识别的综合征，可以与其他影响言语和语言的神经退行性疾病区分开来。
Apraxia of speech (AOS) can be caused by neurodegenerative disease and sometimes is its presenting sign (i.e., primary progressive apraxia of speech, PPAOS). During the last several decades our understanding of PPAOS has evolved from clinical recognition to a fuller understanding of its core and associated clinical features, its distinction from but relationship with primary progressive aphasia, its temporal course and eventual progression to include other neurological deficits, and its neuroimaging correlates and underlying pathology. This paper provides a comprehensive summary of the literature that has built the current knowledge base about PPAOS and progressive AOS as it co-occurs with progressive aphasia. It reviews the history of its emergence as a recognized syndrome; its relationship with the agrammatic/nonfluent variant of primary progressive aphasia; its salient perceptual features and subtypes; the acoustic and structural/physiological imaging measures that index its presence, severity, and distinction from aphasia; and principles and available data regarding its management and care. A broad summary of what is known about AOS as a manifestation of neurodegenerative disease. Primary progressive apraxia of speech is a recognizable syndrome that can be distinguished from other neurodegenerative conditions that affect speech and language.
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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作者：
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作者：
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通讯作者：
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DOI：
10.1590/1980-57642018dn12-010012
发表时间：
2018-01
期刊：
Dementia & neuropsychologia
影响因子：
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作者：
Beber BC;Berbert MCB;Grawer RS;Cardoso MCAF
通讯作者：
Cardoso MCAF