Improving maintenance of physical activity in older, knee osteoarthritis patients trial-pilot (IMPACT-P): design and methods.

Improving maintenance of physical activity in older, knee osteoarthritis patients trial-pilot (IMPACT-P): design and methods.
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DOI:
10.1016/j.cct.2012.04.012
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发表时间:
2012-09
影响因子:
2.2
通讯作者:
Rejeski WJ
Rejeski WJ
中科院分区:
医学4区
文献类型:
--
作者:
Focht BC;Garver MJ;Devor ST;Dials J;Rose M;Lucas AR;Emery CF;Hackshaw K;Rejeski WJ

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在膝关节骨关节炎(OA)的医疗管理中,现在一直提倡增加体力活动的参与。不幸的是,针对老年膝关节OA患者的体力活动干预受到高损耗率和长期依从性差的困扰。因此,确定有效的方法来促进维持身体活动的参与是不可或缺的成功的膝关节骨性关节炎的行为管理。目前的研究,改善维持体力活动在膝关节骨关节炎试点试验(IMPACT-P),是一个单盲,两个手臂,随机对照试点研究,旨在对比的效果,群体介导的认知行为(GMCB)运动干预与传统的中心为基础的运动治疗方法(TRAD)在老年人,膝关节OA患者。共有80名患有症状性膝关节OA的老年人被随机分配接受GMCB或TRAD干预。IMPACT-P研究的主要结局是自我报告(CHAMPS问卷)和客观评估(LIFECORDER EX Plus)中等强度或更高强度体力活动参与的变化。次要结果包括身体功能、生活质量和社会认知变量。在基线、3个月和12个月评估时,由对受试者随机分配不知情的试验人员获得结局。确定GMCB和TRAD运动干预在产生有意义的身体活动和OA结局改善方面的可比疗效,可以提高在症状性膝关节OA的行为管理中实施身体活动参与的疗效。
Promoting increased physical activity participation is now consistently advocated in the medical management of knee osteoarthritis (OA). Unfortunately, physical activity interventions targeting older knee OA patients are plagued by high attrition rates and poor long-term adherence. Consequently, identifying effective approaches for promoting maintenance of physical activity participation is integral for the successful behavioral management of knee OA. The present study, the Improving Maintenance of Physical Activity in Knee Osteoarthritis Pilot Trial (IMPACT-P), was a single-blind two-arm, randomized controlled pilot study designed to contrast the effects of a group-mediated cognitive behavioral (GMCB) exercise intervention with those of traditional center-based exercise therapy approach (TRAD) in older, knee OA patients. A total of 80 older adults with symptomatic knee OA were randomly assigned to GMCB or TRAD interventions. The primary outcome of the IMPACT-P study was change in self-reported (CHAMPS questionnaire) and objectively assessed (LIFECORDER EX Plus) physical activity participation of moderate intensity or greater. Secondary outcomes include physical function, quality of life, and social cognitive variables. Outcomes were obtained at baseline, 3 month, and 12 month assessments by trial personnel blinded to participants’ randomization assignment. Determining the comparable efficacy of the GMCB and TRAD exercise interventions in producing meaningful improvements in physical activity and OA outcomes could enhance the efficacy of implementing physical activity participation in the behavioral management of symptomatic knee OA.
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