Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic.
Evaluating Barriers to Viral Suppression among People with HIV in Santiago, Dominican Republic.
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DOI：
10.1177/23259582221096522
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发表时间：
2022-01
影响因子：
--
通讯作者：
Sanchez, Martha C.
中科院分区：
文献类型：
--
作者：
McCarthy, Meghan;Tao, Jun;Lerebours, Alain;Rodriguez, Claudia;Flanigan, Timothy P.;Sanchez, Martha C.
多米尼加共和国（DR）是加勒比地区艾滋病毒感染率第二高的国家，但病毒抑制和治疗依从性尚不清楚。我们在艾滋病毒/艾滋病感染者（PLWHA）中进行了一项横断面研究，以填补知识空白。问卷调查被用来收集人口统计学数据，抗逆转录病毒治疗（ART）的依从性，艾滋病毒护理的障碍和促进因素。通过病历审查提取病毒载量和其他临床信息。进行描述性分析和logistic回归，以探讨与非病毒抑制和不完善的ART依从性相关的因素。在193例PLWHA中，83.9%的病毒被抑制。那些非病毒抑制的人更有可能是男性（比值比[OR]：2.55，95%置信区间[CI]：1.17-5.58），失业的可能性更小（OR：0.28，95% CI：0.08-0.96）。然而，男性（OR：0. 78，95% CI：0. 40 - 1. 53）和失业者（OR：0. 28，95% CI：0. 40 - 1. 53）。08-1.21）不太可能报告不完美的依从性。需要量身定制的干预措施来改善DR的依从性和病毒抑制。
The Dominican Republic (DR) has the second-highest prevalence of HIV infection in the Caribbean, but viral suppression and treatment adherence are not well understood. We conducted a cross-sectional study among people living with HIV/AIDS(PLWHA) to fill in the knowledge gap. Questionnaire was used to collect demographic data, antiretroviral therapy (ART) adherence, and barriers and facilitators to HIV care. Viral load and other clinical information were extracted through chart reviews. Descriptive analyzes and logistic regression were conducted to explore factors associated with non-viral suppression and imperfect ART adherence. Of 193 PLWHA 83.9% were virally suppressed. Those that were non-virally suppressed were more likely of being male (odds ratio [OR]: 2.55, 95% confidence interval [CI]: 1.17-5.58) and less likely of being unemployed (OR: 0.28, 95% CI: 0.08-0.96). However, being male (OR: 0.78, 95% CI:0.40-1.53) and unemployed (OR: 0.28, 95% CI:0. 08-1.21) were less likely to report imperfect adherence. Tailored interventions are needed to improve adherence and viral suppression in DR.
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作者：
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DOI：
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DOI：
10.1016/s2352-3018(20)30358-1
发表时间：
2021-05
期刊：
The lancet. HIV
影响因子：
--
作者：
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通讯作者：
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