Ordered Microdomain Structures in Saccharide-Polystyrene-Saccharide Hybrid Conjugates.
Ordered Microdomain Structures in Saccharide-Polystyrene-Saccharide Hybrid Conjugates.
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糖-聚苯乙烯-糖混合缀合物中的有序微域结构。
DOI：
10.1021/acs.biomac.1c00931
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发表时间：
2021
影响因子：
6.2
通讯作者：
Sheng Li
中科院分区：
文献类型：
--
作者：
Minji Seo;Hayeon Kim;Eunji Lee;Sheng Li
混合缀合物由合成聚合物和天然存在的糖组成，能够在小分子量下进行微相分离，形成有序的域结构。在本研究中，我们合成了 ABA 三嵌段样缀合物，其中聚苯乙烯作为合成的中间段，三糖麦芽三糖 (MT) 或二糖麦芽糖 (Mal) 作为末端单元。通过原子转移自由基聚合和点击反应的结合制备了不同组成的混合缀合物，并通过小角 X 射线散射和透射电子显微镜检查了它们的形态。发现含有 MT 的缀合物形成具有亚 10 nm 周期性的有序域结构，并且随着糖重量分数的降低，观察到从圆柱体到球体再到无序球体的形态转变。含有Mal的缀合物也表现出微相分离。然而，由于聚合物玻璃化转变温度和有序-无序转变温度非常接近，观察到的域形态缺乏规则堆积。还发现含糖缀合物在高温下经历不可逆的形态变化，这归因于糖脱水诱导的五嵌段样结构的形成。
Hybrid conjugates consist of synthetic polymers and naturally occurring saccharides, and are capable of microphase separation at small molecular weights to form ordered domain structures. In this study, we synthesize ABA triblock-like conjugates with polystyrene as the synthetic mid-segment and either trisaccharide maltotriose (MT) or disaccharide maltose (Mal) as the end unit. Hybrid conjugates of varying compositions are prepared by a combination of atom transfer radical polymerization and a click reaction, and their morphologies are examined by small-angle X-ray scattering and transmission electron microscopy. The MT-containing conjugates are found to form well-ordered domain structures with a sub-10 nm periodicity, and morphology transition from cylinders to spheres to disordered spheres is observed with decreasing saccharide weight fraction. The Mal-containing conjugates also show microphase separation. However, the observed domain morphologies lack regular packing due to the close proximity of polymer glass transition temperature and order-disorder transition temperature. The saccharide-containing conjugates are also found to undergo an irreversible morphology change at high temperatures, attributed to saccharide dehydration-induced pentablock-like structure formation.
影响因子：
5.5
作者：
Kohei Yoshida;S. Tanaka;Takuya Yamamoto;K. Tajima;R. Borsali;Takuya Isono;T. Satoh
通讯作者：
Kohei Yoshida;S. Tanaka;Takuya Yamamoto;K. Tajima;R. Borsali;Takuya Isono;T. Satoh
影响因子：
3.9
作者：
Otsuka, Issei;Fuchise, Keita;Borsali, Redouane
通讯作者：
Borsali, Redouane