miRNAs in B Cell Development and Lymphomagenesis.

miRNAs in B Cell Development and Lymphomagenesis.
复制标题

B 细胞发育和淋巴瘤发生中的 miRNA。

DOI:
10.1016/j.molmed.2017.06.001
复制
发表时间:
2017-08
影响因子:
13.6
通讯作者:
Koralov SB
Koralov SB
中科院分区:
医学1区
文献类型:
--
作者:
Coffre M;Koralov SB

文献摘要

参考文献

被引文献

相似文献

B淋巴细胞对于对抗各种病原体的有效免疫反应是必不可少的。很大一部分血液系统恶性肿瘤起源于B细胞,这表明B细胞的发育和激活需要受到严格的调控。近年来,越来越多的证据表明,microRNAs(MiRNAs)--一类控制基因表达的非编码RNA--参与了B细胞的发育和功能的调节。在此,我们就miRNAs及其相关靶点在B细胞发育、B细胞激活和B细胞恶性转化中的作用作一综述。
B lymphocytes are essential for an efficient immune response against a variety of pathogens. A large fraction of hematologic malignancies is of B cell origin suggesting that development and activation of B cells need to be tightly regulated. In recent years, increasing evidence has emerged demonstrating that microRNAs (miRNAs) -- a class of non-coding RNAs that control gene expression -- are involved in the regulation of B cell development and function. Here, we provide an overview of the current knowledge on the role of miRNAs and their relevant targets in B cell development, B cell activation and B cell malignant transformation.
DOI: 10.1038/nature07242
发表时间: 2008-09-04
期刊: NATURE
影响因子: 64.8
作者:
Baek, Daehyun;Villen, Judit;Shin, Chanseok;Camargo, Fernando D.;Gygi, Steven P.;Bartel, David P.
通讯作者: Bartel, David P.
DOI: 10.1016/j.leukres.2014.12.002
发表时间: 2015-03
期刊: Leukemia research
影响因子: 2.7
作者:
Danielson LS;Reavie L;Coussens M;Davalos V;Castillo-Martin M;Guijarro MV;Coffre M;Cordon-Cardo C;Aifantis I;Ibrahim S;Liu C;Koralov SB;Hernando E
通讯作者: Hernando E
DOI: 10.1038/ni.3385
发表时间: 2016-04
期刊: Nature immunology
影响因子: 30.5
作者:
Gonzalez-Martin A;Adams BD;Lai M;Shepherd J;Salvador-Bernaldez M;Salvador JM;Lu J;Nemazee D;Xiao C
通讯作者: Xiao C
具有受限BCR的早期生成的B1 B细胞成为持续C-MYC和低BMF表达的慢性淋巴细胞性白血病。
DOI: 10.1084/jem.20160712
发表时间: 2016-12-12
期刊: The Journal of experimental medicine
影响因子: --
作者:
Hayakawa K;Formica AM;Brill-Dashoff J;Shinton SA;Ichikawa D;Zhou Y;Morse HC 3rd;Hardy RR
通讯作者: Hardy RR
DOI: 10.4049/jimmunol.1102479
发表时间: 2011-12-01
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Duong BH;Ota T;Aoki-Ota M;Cooper AB;Ait-Azzouzene D;Vela JL;Gavin AL;Nemazee D
通讯作者: Nemazee D