Strategies to increase access to basic sickle cell disease care in low- and middle-income countries.
Strategies to increase access to basic sickle cell disease care in low- and middle-income countries.
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DOI：
10.1080/17474086.2022.2063116
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发表时间：
2022-04
影响因子：
2.8
通讯作者：
Estepp, Jeremie H.
中科院分区：
文献类型：
--
作者：
Dua, Meghna;Bello-Manga, Halima;Carroll, Yvonne M.;Galadanci, Aisha Amal;Ibrahim, Umma Abdulsalam;King, Allison A.;Olanrewaju, Ayobami;Estepp, Jeremie H.
关键词：
镰状细胞病（SCD）是世界上最常见的血红蛋白病。超过90%的SCD患者生活在低收入和中等收入国家（LMICs），但与高收入国家相比，这些国家的个人的结果要差得多。这份手稿提供了一个深入的审查基本SCD护理的基石，在低收入国家实施这些障碍，并在这些地区增加访问的战略。在PubMed上识别了2000年至2021年期间的英文、同行评审和编辑出版物。谷歌搜索被用于灰色文献。在过去的几十年里，由于实施了普遍的新生儿筛查计划和使用常规的抗生素预防，增加了治疗和治愈选择，以及采取了降低卒中风险的具体措施，高收入国家SCD患者的结局有所改善。由于包括资源限制在内的若干原因，这一成功没有转化为中低收入国家。需要结合几种策略来增加这些环境中患者获得基本SCD护理的机会。
Sickle cell disease (SCD) is the most common hemoglobinopathy in the world. Over 90% of those born with SCD live in low- and middle-income countries (LMICs), yet individuals in these settings have much poorer outcomes compared to those in high-income countries. This manuscript provides an in-depth review of the cornerstones of basic SCD care, the barriers to implementing these in LMICs, and strategies to increase access in these regions. Publications in English language, peer-reviewed, and edited from 2000 to 2021 were identified on PubMed. Google search was used for gray literature. Outcomes for patients with SCD in high-income countries have improved over the last few decades due to the implementation of universal newborn screening programs and use of routine antimicrobial prophylaxis, increase in therapeutic and curative options, and the adoption of specific measures to decrease risk of stroke. This success has not translated to LMICs due to several reasons including resource constraints. A combination of several strategies is needed to increase access to basic SCD care for patients in these settings.
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DOI：
10.4084/mmid.2010.014
发表时间：
2010-01-01
影响因子：
3.2
作者：
Ahmed, Sagir G.;Bukar, Audu A.;Jolayemi, Bashir
通讯作者：
Jolayemi, Bashir
影响因子：
1.9
作者：
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影响因子：
8
作者：
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通讯作者：
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影响因子：
12.8
作者：
Costa E;Tibalinda P;Sterzi E;Leufkens HMG;Makani J;Kaale E;Luzzatto L
通讯作者：
Luzzatto L
影响因子：
3.2
作者：
Diallo, D;Tchernia, G
通讯作者：
Tchernia, G