Characterizing the dynamics underlying global spread of epidemics.
Characterizing the dynamics underlying global spread of epidemics.
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DOI:
10.1038/s41467-017-02344-z
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发表时间:
2018-01-15
影响因子:
16.6
通讯作者:
Wu JT
中科院分区:
文献类型:
--
作者:
Wang L;Wu JT
Over the past few decades, global metapopulation epidemic simulations built with worldwide air-transportation data have been the main tool for studying how epidemics spread from the origin to other parts of the world (e.g., for pandemic influenza, SARS, and Ebola). However, it remains unclear how disease epidemiology and the air-transportation network structure determine epidemic arrivals for different populations around the globe. Here, we fill this knowledge gap by developing and validating an analytical framework that requires only basic analytics from stochastic processes. We apply this framework retrospectively to the 2009 influenza pandemic and 2014 Ebola epidemic to show that key epidemic parameters could be robustly estimated in real-time from public data on local and global spread at very low computational cost. Our framework not only elucidates the dynamics underlying global spread of epidemics but also advances our capability in nowcasting and forecasting epidemics. Understanding global epidemics spread is crucial for preparedness and response. Here the authors introduce an analytical framework to study epidemic spread on air transport networks, and demonstrate its power to estimate key epidemic parameters by application to the recent influenza pandemic and Ebola outbreak.
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DOI:
10.1073/pnas.0906910106
发表时间:
2009-12-22
影响因子:
11.1
作者:
Balcan, Duygu;Colizza, Vittoria;Vespignani, Alessandro
通讯作者:
Vespignani, Alessandro
DOI:
10.1056/nejmoa1411100
发表时间:
2014-10-16
期刊:
The New England journal of medicine
影响因子:
--
作者:
WHO Ebola Response Team;Aylward B;Barboza P;Bawo L;Bertherat E;Bilivogui P;Blake I;Brennan R;Briand S;Chakauya JM;Chitala K;Conteh RM;Cori A;Croisier A;Dangou JM;Diallo B;Donnelly CA;Dye C;Eckmanns T;Ferguson NM;Formenty P;Fuhrer C;Fukuda K;Garske T;Gasasira A;Gbanyan S;Graaff P;Heleze E;Jambai A;Jombart T;Kasolo F;Kadiobo AM;Keita S;Kertesz D;Koné M;Lane C;Markoff J;Massaquoi M;Mills H;Mulba JM;Musa E;Myhre J;Nasidi A;Nilles E;Nouvellet P;Nshimirimana D;Nuttall I;Nyenswah T;Olu O;Pendergast S;Perea W;Polonsky J;Riley S;Ronveaux O;Sakoba K;Santhana Gopala Krishnan R;Senga M;Shuaib F;Van Kerkhove MD;Vaz R;Wijekoon Kannangarage N;Yoti Z
通讯作者:
Yoti Z
影响因子:
3.7
作者:
Bobashev G;Morris RJ;Goedecke DM
通讯作者:
Goedecke DM
DOI:
10.1073/pnas.0308344101
发表时间:
2004-10-19
影响因子:
11.1
作者:
Hufnagel, L;Brockmann, D;Geisel, T
通讯作者:
Geisel, T
影响因子:
56.9
作者:
Brockmann, Dirk;Helbing, Dirk
通讯作者:
Helbing, Dirk