Defining recurrent implantation failure: a profusion of confusion or simply an illusion?
Defining recurrent implantation failure: a profusion of confusion or simply an illusion?
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DOI:
10.1016/j.fertnstert.2021.10.023
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发表时间:
2021-12
影响因子:
6.7
通讯作者:
Young SL
中科院分区:
文献类型:
--
作者:
Garneau AS;Young SL
Recurrent implantation failure (RIF) is a poorly defined clinical scenario marked by failure to achieve pregnancy after multiple embryo transfers. The causes and definitions of implantation failure are heterogenous, posing limitations on study design as well as the interpretation and application of findings. Recent studies suggest a novel, personalized approach to defining RIF. Here, we will review implantation physiology and the definitions of implantation rate, failure, and RIF. Current definitions of RIF vary greatly. Future approaches to defining RIF may be personalized based on the presence or absence of risk factors for implantation failure, such as euploidy.
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DOI:
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发表时间:
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期刊:
Human reproduction (Oxford, England)
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