Offense and defense: microbial membrane vesicles play both ways.
Offense and defense: microbial membrane vesicles play both ways.
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DOI：
10.1016/j.resmic.2012.10.020
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发表时间：
2012-11
影响因子：
2.6
通讯作者：
Kuehn, Meta J.
中科院分区：
文献类型：
--
作者：
MacDonald, Ian A.;Kuehn, Meta J.
微生物已经进化了数千年，以适应和专门化它们所占据的环境。这些环境可能包括水或土壤、热液喷口等极端环境，甚至可能包括宿主生物。为了适应这些地方，微生物已经进化出特定的工具来介导与环境的相互作用。原核生物已经进化出的一种这样的工具包括膜囊泡（MV）的产生。MV是源自最外层膜的10-300 nm球形泡，并且在蛋白质分泌、免疫激活和抑制、应激反应、附着、内化和毒力中具有已知功能。在这篇综述中，我们认为来自革兰氏阴性菌，革兰氏阳性菌和古细菌物种的膜囊泡的高度保守的作用，以促进微生物间和微生物-宿主相互作用的机制。我们研究了MV的进攻和防御能力方面的相互作用的MV与宿主和微生物细胞在其环境中。
Microbes have evolved over millennia to become adapted and specialized to the environments that they occupy. These environments may include water or soil, extreme environments such as hydrothermal vents, and can even include a host organism. To become adapted to these locations, microbes have evolved specific tools to mediate interactions with the environment. One such tool that prokaryotes have evolved includes the production of membrane vesicles (MVs). MVs are 10–300 nm spherical blebs derived from the outermost membrane and have known functions in protein secretion, immune activation and suppression, stress response, attachment, internalization and virulence. In this review, we consider the highly conserved role of membrane vesicles derived from Gram-negative, Gram-positive and archaeal species as a mechanism to facilitate intermicrobial and microbe-host interaction. We examine both the offensive and defensive capabilities of MVs in regard to the interaction of MVs with both host and microbial cells in their environment.
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影响因子：
3.5
作者：
Donato GM;Goldsmith CS;Paddock CD;Eby JC;Gray MC;Hewlett EL
通讯作者：
Hewlett EL
DOI：
10.1155/2010/608243
发表时间：
2010-07-07
期刊：
Archaea (Vancouver, B.C.)
影响因子：
--
作者：
Ellen AF;Zolghadr B;Driessen AM;Albers SV
通讯作者：
Albers SV
影响因子：
4.2
作者：
Bauman SJ;Kuehn MJ
通讯作者：
Kuehn MJ
影响因子：
3.1
作者：
Bielig, H.;Rompikuntal, P. K.;Kufer, T. A.
通讯作者：
Kufer, T. A.
影响因子：
3.4
作者：
Choi, Dong-Sic;Kim, Dae-Kyum;Gho, Yong Song
通讯作者：
Gho, Yong Song