Design and methods of a randomized trial testing the novel Wellness Intervention for Smokers Living with HIV (WISH).

Design and methods of a randomized trial testing the novel Wellness Intervention for Smokers Living with HIV (WISH).
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DOI:
10.1016/j.cct.2021.106486
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发表时间:
2021-11
影响因子:
2.2
通讯作者:
Crothers K
Crothers K
中科院分区:
医学4区
文献类型:
--
作者:
McClure JB;Catz SL;Chalal C;Ciuffetelli R;Coggeshall S;DeFaccio RJ;Fleehart S;Heffner JL;Thompson E;Williams EC;Crothers K

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艾滋病毒感染者的吸烟率高得不成比例。感染艾滋病毒的吸烟者(SLWH)在很大程度上也不知道吸烟对艾滋病毒特有的有害影响,而且往往对自己戒烟的能力缺乏动力和信心。为了解决这些问题,我们开发了艾滋病毒感染者吸烟者健康干预(WISH)。WISH基于信息-动机-行为技能(IMB)模型,专为所有SLWH设计,无论他们最初的戒烟动机如何。它遵循尼古丁依赖治疗的循证最佳实践指南,但在使用全面健康方法方面具有创新性,该方法在艾滋病毒自我管理的背景下解决吸烟问题,包括治疗依从性和参与,压力管理,物质使用和其他个人相关的健康行为目标。所描述的随机试验将招募在退伍军人事务部(VA)医疗中心接受护理的SLWH,并将WISH对吸烟行为的影响与通过国家VA Quitline和SmokefreeVET短信计划提供的标准护理服务进行比较。它还将评估干预措施对免疫状态和死亡风险标志物的影响。如果有效的话,WISH可以传播给全国的退伍军人,并可以作为一个模型,为其他对戒烟犹豫不决的吸烟者设计戒烟干预措施。本文概述了WISH试验的原理和方法,该试验是最近由美国国家癌症研究所资助的一系列研究之一,旨在促进对如何更好地促进SLWH戒烟的理解。
Smoking rates are disproportionately high among people living with HIV. Smokers living with HIV (SLWH) are also largely unaware of the HIV-specific deleterious effects of smoking and often lack motivation and confidence in their ability to quit tobacco. To address these issues, we developed the Wellness Intervention for Smokers Living with HIV (WISH). WISH is grounded in the Information-Motivation-Behavioral Skills (IMB) Model and is designed for all SLWH, regardless of their initial motivation to quit. It follows evidence-based, best practice guidelines for nicotine dependence treatment, but is innovative in its use of a comprehensive wellness approach that addresses smoking within the context of HIV self-management including treatment adherence and engagement, stress management, substance use, and other personally relevant health behavior goals. The described randomized trial will enroll SLWH who are receiving care at Veterans Affairs (VA) medical centers and compare WISH’s impact on smoking behavior to standard care services offered through the National VA Quitline and SmokefreeVET texting program. It will also assess intervention impact on markers of immune status and mortality risk. If effective, WISH could be disseminated to Veterans nationwide and could serve as a model for designing quitline interventions for other smokers who are ambivalent about quitting. The current paper outlines the rationale and methodology of the WISH trial, one of a series of studies recently funded by the National Cancer Institute to advance understanding of how to better promote smoking cessation among SLWH.
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