Retinotopic connectivity maps of human visual cortex with unconstrained eye movements.
Retinotopic connectivity maps of human visual cortex with unconstrained eye movements.
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DOI:
10.1002/hbm.26446
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发表时间:
2023-11
影响因子:
4.8
通讯作者:
Schwarzkopf, D. Samuel
中科院分区:
文献类型:
--
作者:
Tangtartharakul, Gene;Morgan, Catherine A.;Rushton, Simon K.;Schwarzkopf, D. Samuel
关键词:
Human visual cortex contains topographic visual field maps whose organization can be revealed with retinotopic mapping. Unfortunately, constraints posed by standard mapping hinder its use in patients, atypical subject groups, and individuals at either end of the lifespan. This severely limits the conclusions we can draw about visual processing in such individuals. Here, we present a novel data‐driven method to estimate connective fields, resulting in fine‐grained maps of the functional connectivity between brain areas. We find that inhibitory connectivity fields accompany, and often surround facilitatory fields. The visual field extent of these inhibitory subfields falls off with cortical magnification. We further show that our method is robust to large eye movements and myopic defocus. Importantly, freed from the controlled stimulus conditions in standard mapping experiments, using entertaining stimuli and unconstrained eye movements our approach can generate retinotopic maps, including the periphery visual field hitherto only possible to map with special stimulus displays. Generally, our results show that the connective field method can gain knowledge about retinotopic architecture of visual cortex in patients and participants where this is at best difficult and confounded, if not impossible, with current methods. Retinotopic maps derived using connective field mapping are robust to the detrimental effects of eye movements in conventional mapping experiments. Data collected while participants play an engaging video game can map the representation of the far peripheral visual field.
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影响因子:
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作者:
Moutsiana C;de Haas B;Papageorgiou A;van Dijk JA;Balraj A;Greenwood JA;Schwarzkopf DS
通讯作者:
Schwarzkopf DS
影响因子:
--
作者:
Morgan, Catherine;Schwarzkopf, D Samuel
通讯作者:
Schwarzkopf, D Samuel
影响因子:
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通讯作者:
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通讯作者:
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通讯作者:
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