Ensembl 2018.
Ensembl 2018.
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DOI：
10.1093/nar/gkx1098
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发表时间：
2018-01-04
影响因子：
14.9
通讯作者：
Flicek P
中科院分区：
文献类型：
--
作者：
Zerbino DR;Achuthan P;Akanni W;Amode MR;Barrell D;Bhai J;Billis K;Cummins C;Gall A;Girón CG;Gil L;Gordon L;Haggerty L;Haskell E;Hourlier T;Izuogu OG;Janacek SH;Juettemann T;To JK;Laird MR;Lavidas I;Liu Z;Loveland JE;Maurel T;McLaren W;Moore B;Mudge J;Murphy DN;Newman V;Nuhn M;Ogeh D;Ong CK;Parker A;Patricio M;Riat HS;Schuilenburg H;Sheppard D;Sparrow H;Taylor K;Thormann A;Vullo A;Walts B;Zadissa A;Frankish A;Hunt SE;Kostadima M;Langridge N;Martin FJ;Muffato M;Perry E;Ruffier M;Staines DM;Trevanion SJ;Aken BL;Cunningham F;Yates A;Flicek P
自人类基因组初稿发布以来，Ensembl项目一直在汇总、处理、整合和重新分配基因组数据集，旨在通过快速开放公共数据来加速基因组学研究。因此，大量的原始数据被转化为知识，这些知识可以通过多种渠道获得，特别是我们的浏览器（http://www.ensembl.org）。随着时间的推移，我们向多个方向扩张。首先，我们的资源描述了基因组学的多个领域，特别是基因注释、比较基因组学、遗传学和表观基因组学。其次，我们涵盖了越来越多的基因组组合；Ensembl Release 90恰好包含100。第三，我们的数据库同时提供一系列针对不同用例设计的服务，从快速浏览到全基因组生物信息学分析。我们在这里介绍了Ensembl项目的最新进展，重点是管理越来越多的组装，支持基因组解释的努力和改进我们的浏览器。
The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded in multiple directions. First, our resources describe multiple fields of genomics, in particular gene annotation, comparative genomics, genetics and epigenomics. Second, we cover a growing number of genome assemblies; Ensembl Release 90 contains exactly 100. Third, our databases feed simultaneously into an array of services designed around different use cases, ranging from quick browsing to genome-wide bioinformatic analysis. We present here the latest developments of the Ensembl project, with a focus on managing an increasing number of assemblies, supporting efforts in genome interpretation and improving our browser.
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影响因子：
12.3
作者：
McLaren W;Gil L;Hunt SE;Riat HS;Ritchie GR;Thormann A;Flicek P;Cunningham F
通讯作者：
Cunningham F
影响因子：
14.9
作者：
Cochrane G;Karsch-Mizrachi I;Takagi T;International Nucleotide Sequence Database Collaboration
通讯作者：
International Nucleotide Sequence Database Collaboration
影响因子：
7
作者：
Harrow J;Frankish A;Gonzalez JM;Tapanari E;Diekhans M;Kokocinski F;Aken BL;Barrell D;Zadissa A;Searle S;Barnes I;Bignell A;Boychenko V;Hunt T;Kay M;Mukherjee G;Rajan J;Despacio-Reyes G;Saunders G;Steward C;Harte R;Lin M;Howald C;Tanzer A;Derrien T;Chrast J;Walters N;Balasubramanian S;Pei B;Tress M;Rodriguez JM;Ezkurdia I;van Baren J;Brent M;Haussler D;Kellis M;Valencia A;Reymond A;Gerstein M;Guigó R;Hubbard TJ
通讯作者：
Hubbard TJ
影响因子：
14.9
作者：
Hubbard, T;Barker, D;Clamp, M
通讯作者：
Clamp, M
影响因子：
4.4
作者：
Chen Y;Cunningham F;Rios D;McLaren WM;Smith J;Pritchard B;Spudich GM;Brent S;Kulesha E;Marin-Garcia P;Smedley D;Birney E;Flicek P
通讯作者：
Flicek P