Mammary gland development from a single cell 'omics view.

Mammary gland development from a single cell 'omics view.
复制标题

DOI:
10.1016/j.semcdb.2021.03.013
复制
发表时间:
2021-06
影响因子:
7.3
通讯作者:
Khaled WT
Khaled WT
中科院分区:
生物学2区
文献类型:
--
作者:
Twigger AJ;Khaled WT

文献摘要

参考文献

被引文献

相似文献

了解乳腺细胞亚群的复杂性和异质性对于阐明乳腺癌发生、发展和预防的机制至关重要。用于研究这些细胞亚型的日益复杂的工具使人们对这些细胞亚型、某些亚型的复杂相互作用及其发展潜力有了更深入的了解。值得注意的是,单细胞技术的可及性和可负担性的提高导致了大量研究的发表,其中包含来自乳腺细胞亚型及其在小鼠和人类数据集中的分化潜力的数据。在这里,我们回顾了不同类型的单细胞技术,以及它们如何用于提高我们对乳腺发育的理解。
Understanding the complexity and heterogeneity of mammary cell subpopulations is vital to delineate the mechanisms behind breast cancer development, progression and prevention. Increasingly sophisticated tools for investigating these cell subtypes has led to the development of a greater understanding of these cell subtypes, complex interplay of certain subtypes and their developmental potential. Of note, increasing accessibility and affordability of single cell technologies has led to a plethora of studies being published containing data from mammary cell subtypes and their differentiation potential in both mice and human data sets. Here, we review the different types of single cell technologies and how they have been used to improve our understanding of mammary gland development.
DOI: 10.1016/j.ccell.2018.08.001
发表时间: 2018-09-10
期刊: Cancer cell
影响因子: 50.3
作者:
Dravis C;Chung CY;Lytle NK;Herrera-Valdez J;Luna G;Trejo CL;Reya T;Wahl GM
通讯作者: Wahl GM
DOI: 10.1038/s41467-021-21783-3
发表时间: 2021-03-09
影响因子: 16.6
作者:
Bach K;Pensa S;Zarocsinceva M;Kania K;Stockis J;Pinaud S;Lazarus KA;Shehata M;Simões BM;Greenhalgh AR;Howell SJ;Clarke RB;Caldas C;Halim TYF;Marioni JC;Khaled WT
通讯作者: Khaled WT
DOI: 10.1038/s41467-017-00244-w
发表时间: 2017-08-09
影响因子: 16.6
作者:
Gao R;Kim C;Sei E;Foukakis T;Crosetto N;Chan LK;Srinivasan M;Zhang H;Meric-Bernstam F;Navin N
通讯作者: Navin N
DOI: 10.1126/science.1198704
发表时间: 2011-05-06
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Bendall SC;Simonds EF;Qiu P;Amir el-AD;Krutzik PO;Finck R;Bruggner RV;Melamed R;Trejo A;Ornatsky OI;Balderas RS;Plevritis SK;Sachs K;Pe'er D;Tanner SD;Nolan GP
通讯作者: Nolan GP
DOI: 10.1038/s41588-019-0424-9
发表时间: 2019-06-01
期刊: NATURE GENETICS
影响因子: 30.8
作者:
Grosselin, Kevin;Durand, Adeline;Gerard, Annabelle
通讯作者: Gerard, Annabelle