Exercise as a Treatment for Schizophrenia: A Review.
Exercise as a Treatment for Schizophrenia: A Review.
复制标题
运动治疗精神分裂症：综述。
作者：
S. Girdler;Jamie E. Confino;M. Woesner
精神分裂症是一种精神障碍，其特征在于在注意力、工作记忆和执行功能方面的进行性认知障碍。虽然没有发现精神分裂症的明确病因，但已经确定了许多有助于疾病发展的因素，如神经递质改变，突触可塑性降低和海马体积减小。历史上，抗精神病药物针对精神分裂症患者大脑中的生化改变，但在缓解认知和海马缺陷方面无效。其他方式，如运动疗法，已被提议作为辅助或主要治疗选择。运动疗法已被证明可以改善精神分裂症患者的阳性和阴性症状、生活质量、认知和海马可塑性，并增加其大脑中的海马体积。本文将简要回顾精神分裂症的临床体征，症状和提出的病因，并描述了目前的理解，运动计划作为一种有效的治疗方法，在患者的疾病。
Schizophrenia is a mental disorder that is characterized by progressive cognitive impairment in areas of attention, working memory, and executive functioning. Although no clear etiology of schizophrenia has been discovered, many factors have been identified that contribute to the development of the disease, such as neurotransmitter alterations, decreased synaptic plasticity, and diminished hippocampal volume. Historically, antipsychotic medications have targeted biochemical alterations in the brains of patients with schizophrenia but have been ineffective in alleviating cognitive and hippocampal deficits. Other modalities, such as exercise therapy, have been proposed as adjuvant or primary therapy options. Exercise therapy has been shown to improve positive and negative symptoms, quality of life, cognition, and hippocampal plasticity, and to increase hippocampal volume in the brains of patients with schizophrenia. This article will briefly review the clinical signs, symptoms and proposed etiologies of schizophrenia, and describe the current understanding of exercise programs as an effective treatment in patients with the disease.
影响因子：
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作者：
Gur, RE;Turetsky, BI;Gur, RC
通讯作者：
Gur, RC
影响因子：
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作者：
Glantz, LA;Lewis, DA
通讯作者：
Lewis, DA