Community health care: therapeutic opportunities in the human microbiome.

Community health care: therapeutic opportunities in the human microbiome.
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DOI:
10.1126/scitranslmed.3001626
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发表时间:
2011-04-13
影响因子:
17.1
通讯作者:
Fischbach MA
Fischbach MA
中科院分区:
医学1区
文献类型:
--
作者:
Sonnenburg JL;Fischbach MA

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我们永远不会孤单。人类与生活在我们体内和体表的各种微生物物种共存-我们所谓的微生物群。现在很明显,这个微生物群落本质上是另一个在人类生理和疾病中发挥重要作用的器官。基础和转化研究工作已经开始集中在破译微生物组功能的机制上,并学习如何操纵它以造福人类健康。在这个角度,我们讨论了人类微生物组的治疗机会。
We are never alone. Humans coexist with diverse microbial species that live within and upon us—our so-called microbiota. It is now clear that this microbial community is essentially another organ that plays a fundamental role in human physiology and disease. Basic and translational research efforts have begun to focus on deciphering mechanisms of microbiome function—and learning how to manipulate it to benefit human health. In this Perspective, we discuss therapeutic opportunities in the human microbiome.
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