DISTURBANCES IN ENDOTHELIAL INTEGRITY

DISTURBANCES IN ENDOTHELIAL INTEGRITY
复制标题

内皮完整性紊乱

DOI:
10.1111/j.1749-6632.1982.tb25721.x
复制
发表时间:
1982
影响因子:
5.2
通讯作者:
S. Schwartz
S. Schwartz
中科院分区:
综合性期刊3区
文献类型:
--
作者:
S. Schwartz

文献摘要

参考文献

被引文献

相似文献

直到最近,血管完整性的概念围绕着血管作为一个连续的非血栓形成,半透性管的想法。随着人们认识到内皮细胞损伤可导致平滑肌增生,这种情况发生了变化。从那时起,细胞培养研究教会了我们很多关于内皮功能的知识,我们在生化水平上发展了内皮功能障碍的新概念。然而,在试管中识别这种损伤是有问题的。虽然形态学研究经常在体外发现“损伤细胞”,但损伤的性质仍不清楚。在这篇综述中,我们将回顾内皮损伤的证据,并描述支持和定义其在体外存在的新数据。
Until recently, concepts of vascular integrity centered around the idea of the blood vessel as a continuous nonthrombogenic, semipermeable tube. This changed with the recognition that damage to the endothelium could lead to smooth muscle proliferation.1-4 Since that time, cell culture studies have taught us a great deal about endothelial function, and we have developed new concepts of endothelial dysfunction at the biochemical level. Identification of such injuries in uivo, however, is problematic. While morphologic studies have frequently identified "injured cells in uivo, the nature of the injury remains unclear. In this overview we would like to review the evidence for endothelial injury and describe new data supporting and defining its presence in uivo.
DOI: --
发表时间: 1981
期刊: Laboratory investigation; a journal of technical methods and pathology
影响因子: --
作者:
Reidy,MA;Schwartz,SM
通讯作者: Schwartz,SM
高血压中的平滑肌细胞肥大与增生。
DOI: 10.1073/pnas.78.12.7759
发表时间: 1981
影响因子: 11.1
作者:
Owens,GK;Rabinovitch,PS;Schwartz,SM
通讯作者: Schwartz,SM
DOI: 10.1161/01.atv.1.2.107
发表时间: 1981-03
期刊: Arteriosclerosis
影响因子: --
作者:
S. Schwartz;C. Gajdusek;S. Selden
通讯作者: S. Schwartz;C. Gajdusek;S. Selden