Attention reduces stimulus-driven gamma frequency oscillations and spike field coherence in V1.
Attention reduces stimulus-driven gamma frequency oscillations and spike field coherence in V1.
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DOI：
10.1016/j.neuron.2010.03.013
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发表时间：
2010-04-15
期刊：
影响因子：
16.2
通讯作者：
Thiele A
中科院分区：
文献类型：
--
作者：
Chalk M;Herrero JL;Gieselmann MA;Delicato LS;Gotthardt S;Thiele A
神经元系综的节律活动在注意、知觉和记忆等认知功能中起着重要作用。在这里，我们调查是否在V1的猕猴（macaca mulatta）的节奏活动的影响，由上而下的视觉注意。我们测量了局部场电位（LFP）和V1尖峰活动，而猴子进行了注意力要求检测任务。我们发现，伽马振荡强烈调制的刺激和注意。参与抑制机制的刺激诱导了最大的γ LFP振荡和最大的尖峰场相干性。将注意力引导到记录神经元感受野的视觉刺激会降低LFP伽马功率和伽马锋电位场相干性。这种减少可能反映了注意力介导的周围抑制的减少。因此，V1的同步性变化可能是抑制性驱动减弱的副产品，而不是直接帮助知觉处理的机制。V1中的伽马同步取决于正常化机制的激活
Rhythmic activity of neuronal ensembles has been proposed to play an important role in cognitive functions such as attention, perception, and memory. Here we investigate whether rhythmic activity in V1 of the macaque monkey (macaca mulatta) is affected by top-down visual attention. We measured the local field potential (LFP) and V1 spiking activity while monkeys performed an attention-demanding detection task. We show that gamma oscillations were strongly modulated by the stimulus and by attention. Stimuli that engaged inhibitory mechanisms induced the largest gamma LFP oscillations and the largest spike field coherence. Directing attention toward a visual stimulus at the receptive field of the recorded neurons decreased LFP gamma power and gamma spike field coherence. This decrease could reflect an attention-mediated reduction of surround inhibition. Changes in synchrony in V1 would thus be a byproduct of reduced inhibitory drive, rather than a mechanism that directly aids perceptual processing. ► Gamma synchronization in V1 depends on activation of normalization mechanisms ► Attention reduces strength of LFP gamma synchronization in V1 ► Attention reduces spike field coherence in V1 ► Increased gamma spike field coherence in is not a universal mechanism of attention
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影响因子：
64.8
作者：
Hupé, JM;James, AC;Bullier, J
通讯作者：
Bullier, J
DOI：
10.1126/science.1171402
发表时间：
2009-05-29
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Gregoriou GG;Gotts SJ;Zhou H;Desimone R
通讯作者：
Desimone R
影响因子：
16.2
作者：
Ozeki, Hirofumi;Finn, Ian M.;Schaffer, Evan S.;Miller, Kenneth D.;Ferster, David
通讯作者：
Ferster, David
影响因子：
64.8
作者：
Herrero, J. L.;Roberts, M. J.;Delicato, L. S.;Gieselmann, M. A.;Dayan, P.;Thiele, A.
通讯作者：
Thiele, A.
影响因子：
2.5
作者：
Disney, Anita A.;Domakonda, Kunal V.;Aoki, Chiye
通讯作者：
Aoki, Chiye