Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments.
Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments.
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DOI:
10.1016/j.cels.2016.07.002
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发表时间:
2016-07
期刊:
影响因子:
9.3
通讯作者:
Aiden EL
中科院分区:
文献类型:
--
作者:
Durand NC;Shamim MS;Machol I;Rao SS;Huntley MH;Lander ES;Aiden EL
Hi-C experiments explore the three-dimensional structure of the genome, generating terabases of data to create high resolution contact maps. Here, we introduce Juicer, an open-source tool for analyzing terabase-scale Hi-C datasets. Juicer allows users without a computational background to transform raw sequence data into normalized contact maps with one click. Juicer produces a hic file containing compressed contact matrices at many resolutions, facilitating visualization and analysis at multiple scales. Structural features, such as loops and domains, are automatically annotated. Juicer is available as open source software at http://aidenlab.org/juicer/
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DOI:
10.1093/bioinformatics/btr064
发表时间:
2011-04-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Grant CE;Bailey TL;Noble WS
通讯作者:
Noble WS
影响因子:
3
作者:
Schmid, Marc W.;Grob, Stefan;Grossniklaus, Ueli
通讯作者:
Grossniklaus, Ueli
影响因子:
12.3
作者:
Servant N;Varoquaux N;Lajoie BR;Viara E;Chen CJ;Vert JP;Heard E;Dekker J;Barillot E
通讯作者:
Barillot E
影响因子:
64.5
作者:
Rao SS;Huntley MH;Durand NC;Stamenova EK;Bochkov ID;Robinson JT;Sanborn AL;Machol I;Omer AD;Lander ES;Aiden EL
通讯作者:
Aiden EL
影响因子:
2.1
作者:
Knight, Philip A.;Ruiz, Daniel
通讯作者:
Ruiz, Daniel