Lung cancer: epidemiology, etiology, and prevention.
Lung cancer: epidemiology, etiology, and prevention.
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DOI：
10.1016/j.ccm.2011.09.001
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发表时间：
2011-12
影响因子：
5.7
通讯作者：
Matthay RA
中科院分区：
文献类型：
--
作者：
Dela Cruz CS;Tanoue LT;Matthay RA
肺癌是美国和世界各地癌症死亡的主要原因。每年死于肺癌的美国人几乎和死于前列腺癌、乳腺癌和结肠癌的人数之和一样多(图1)。1西格尔和他的同事1回顾了最近的癌症数据，估计2010年美国总共有239,320例新的肺癌病例和161,250例肺癌死亡。2统计数据反映的是2007年的数据，因此可能低估了当前的肺癌负担。自1985年以来，肺癌一直是世界上最常见的癌症，无论是发病率还是死亡率。在全球范围内，肺癌是新的癌症诊断(1,350,000新病例，占总癌症病例的12.4%)和癌症死亡(1,180,000例死亡，占总癌症死亡的17.6%)的最大贡献者。美国肺癌的5年生存率为15.6%，尽管在过去的几十年里，肺癌的生存率有所提高，但在其他常见恶性肿瘤中已经实现的生存率进步在肺癌中还没有实现。发展中国家的肺癌病例数量有了较大的相对增长。现在大约一半(49.9%)的病例发生在发展中国家，而在1980年，69%的病例发生在发达国家。据估计，自1985年以来，全球肺癌病例增加了51%(男性增加44%，女性增加76%)。在美国，肺癌和支气管癌在两性中都排在第二位，估计有115,060名男性新病例(占所有新发癌症的14%)和106,070名女性(占所有新发癌症的14%)。1、2在美国，肺癌的年龄调整发病率为每年每10万人中有62人患肺癌，男性的发病率高于女性(75.2/10万比52.3/10万)。3男女肺癌每年的估计死亡人数均居榜首(男性85,600人，占所有癌症死亡人数的28%，女性为71,340人，占所有癌症死亡人数的26%)(图2)。
Lung cancer is the leading cause of cancer death in the United States and around the world. Almost as many Americans die of lung cancer every year than die of prostate, breast, and colon cancer combined (Fig. 1). 1 Siegel and colleagues1 reviewed recent cancer data and estimated a total of 239,320 new cases of lung cancer and 161,250 deaths from lung cancer in the United States in 2010. 2 The statistics reflect data from 2007 and, therefore, likely underestimate the current lung cancer burden. Lung cancer has been the most common cancer worldwide since 1985, both in terms of incidence and mortality. Globally, lung cancer is the largest contributor to new cancer diagnoses (1,350,000 new cases and 12.4% of total new cancer cases) and to death from cancer (1,180,000 deaths and 17.6% of total cancer deaths). The 5-year survival rate in the United States for lung cancer is 15.6%, and although there has been some improvement in survival during the past few decades, the survival advances that have been realized in other common malignancies have yet to be achieved in lung cancer. There has been a large relative increase in the numbers of cases of lung cancer in developing countries. Approximately half (49.9%) of the cases now occur in developing countries whereas in 1980, 69% of cases were in developed countries. The estimated numbers of lung cancer cases worldwide has increased by 51% since 1985 (a 44% increase in men and a 76% increase in women). In the United States, cancer of the lung and bronchus ranks second in both genders, with an estimated 115,060 new cases in men (14% of all new cancers) and 106,070 in women (14% of all new cancers). 1, 2 The age-adjusted incidence rate of lung cancer is 62 per 100,000 men and women per year in the United States, with the incidence rate higher in men than in women (75.2 vs 52.3 per 100,000). 3 Lung cancer in both genders tops the list on the number of estimated deaths yearly (85,600, or 28% of all cancer deaths for men, and 71,340, or 26% of all cancer deaths for women)(Fig. 2).
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影响因子：
10.3
作者：
Barsky, SH;Roth, MD;Tashkin, DP
通讯作者：
Tashkin, DP
DOI：
10.1093/jnci/86.24.1829
发表时间：
1994-12-21
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
ALAVANJA, MCR;BROWNSON, RC;BOICE, JD
通讯作者：
BOICE, JD
影响因子：
30.8
作者：
Bell, DW;Gore, I;Haber, DA
通讯作者：
Haber, DA
影响因子：
4.7
作者：
Benhamou, S;Lee, WJ;Taioli, E
通讯作者：
Taioli, E
影响因子：
5.4
作者：
Bhatia, R;Lopipero, P;Smith, AH
通讯作者：
Smith, AH