Cardiovascular Magnetic Resonance for Patients With COVID-19.

Cardiovascular Magnetic Resonance for Patients With COVID-19.
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DOI:
10.1016/j.jcmg.2021.08.021
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发表时间:
2022-04
期刊:
JACC. Cardiovascular imaging
影响因子:
--
通讯作者:
Bluemke DA
Bluemke DA
中科院分区:
其他
文献类型:
--
作者:
Petersen SE;Friedrich MG;Leiner T;Elias MD;Ferreira VM;Fenski M;Flamm SD;Fogel M;Garg R;Halushka MK;Hays AG;Kawel-Boehm N;Kramer CM;Nagel E;Ntusi NAB;Ostenfeld E;Pennell DJ;Raisi-Estabragh Z;Reeder SB;Rochitte CE;Starekova J;Suchá D;Tao Q;Schulz-Menger J;Bluemke DA

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COVID-19与缺血、炎症或心肌炎引起的心肌损伤有关。心血管磁共振(CMR)是心脏功能、结构和组织成分的无创参考标准。CMR对于出现心肌损伤和心功能不全证据的COVID-19患者是一种潜在的有价值的诊断工具。尽管COVID-19相关心肌炎可能并不常见,但已报告高达48%的患者出现COVID-19相关心血管组织病理学结果,这引起了对长期心肌损伤的担忧。迄今为止的研究报告称,26%至60%的COVID-19康复住院患者出现CMR异常,包括功能障碍、心肌组织异常、晚期钆增强或心包异常。在COVID-19后的运动员中,CMR检测到心肌炎样异常。在儿童中,多系统炎症综合征可能在感染后2 - 6周发生;相关的心肌炎和冠状动脉瘤可通过CMR评估。目前,我们对COVID-19相关心血管受累的了解尚不完整,计划进行多项研究,以使用CMR评估COVID-19患者。在这篇综述中,我们总结了COVID-19患者CMR的现有研究,并介绍了正在进行的研究。我们还为有急性症状或从COVID-19中恢复的患者提供CMR的临床使用建议。
COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19–related myocarditis is likely infrequent, COVID-19–related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial tissue abnormalities, late gadolinium enhancement, or pericardial abnormalities. In athletes post–COVID-19, CMR has detected myocarditis-like abnormalities. In children, multisystem inflammatory syndrome may occur 2 to 6 weeks after infection; associated myocarditis and coronary artery aneurysms are evaluable by CMR. At this time, our understanding of COVID-19–related cardiovascular involvement is incomplete, and multiple studies are planned to evaluate patients with COVID-19 using CMR. In this review, we summarize existing studies of CMR for patients with COVID-19 and present ongoing research. We also provide recommendations for clinical use of CMR for patients with acute symptoms or who are recovering from COVID-19.
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