Biological rhythm development in preterm infants: does health status influence body temperature circadian rhythm?

Biological rhythm development in preterm infants: does health status influence body temperature circadian rhythm?
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早产儿生物节律发育:健康状况影响体温昼夜节律吗?

DOI:
10.1002/nur.1020
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发表时间:
2001
影响因子:
2
通讯作者:
Thomas,KA
Thomas,KA
中科院分区:
医学4区
文献类型:
--
作者:
Thomas,KA

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一项关于体温昼夜节律发展的研究纳入了 26 名早产儿,受孕后年龄为 28 至 35 周,产后年龄约为 14 天。在 24 小时内以 1 分钟的间隔连续记录绝热腹部皮肤温度和培养箱空气温度。使用余弦分析,确定周期中观、振幅和顶相。回归分析的初步结果并未证实受孕后年龄和振幅之间的预测线性关系;然而,根据健康状况将样本分为患病组(N= 15)和未患病组(N= 11),显示了不同的回归模型。对于未患病婴儿,振幅随着受孕后年龄而增加(R2= .405),而在患病婴儿中,受孕后年龄与周期振幅之间没有发现关系(R2= .069)。这些结果表明,健康的早产儿表现出昼夜温度节律的出现。影响包括潜在的基于时间的脆弱性、过热和体温过高以及孵化器操作的管理。 © 2001 John Wiley & Sons, Inc. Res Nurs Health 24: 170–180, 2001
Twenty‐six preterm infants, postconceptional age from 28 to 35 weeks and postnatal age approximately 14 days, were included in a study of the development of temperature circadian rhythm. Insulated abdominal skin temperature and incubator air temperature were recorded continuously at 1‐min intervals for 24 hr. Using cosinor analysis, cycle mesor, amplitude, and acrophase were determined. Initial results from regression analysis did not confirm a predicted linear relationship between postconceptional age and amplitude; however, dividing the sample according to health status into sick (N= 15) and not sick (N= 11) groups revealed differing regression models. For not sick infants, amplitude increased with postconceptional age (R2= .405), whereas no relationship was found between postconceptional age and cycle amplitude in sick infants (R2= .069). These results indicate that healthy preterm infants demonstrate emergence of circadian temperature rhythm. Implications include potential time‐based periods of vulnerability, overheating and hyperthermia, and management of incubator operation. © 2001 John Wiley & Sons, Inc. Res Nurs Health 24: 170–180, 2001
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