Rationale and design of the research project of the South Florida Center for the Reduction of Cancer Health Disparities (SUCCESS): study protocol for a randomized controlled trial.
Rationale and design of the research project of the South Florida Center for the Reduction of Cancer Health Disparities (SUCCESS): study protocol for a randomized controlled trial.
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DOI：
10.1186/1745-6215-15-299
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发表时间：
2014-07-23
期刊：
影响因子：
2.5
通讯作者：
Kobetz E
中科院分区：
文献类型：
--
作者：
Carrasquillo O;McCann S;Amofah A;Pierre L;Rodriguez B;Alonzo Y;Ilangovan K;Gonzalez M;Trevil D;Byrne MM;Koru-Sengul T;Kobetz E
在美国，某些少数群体，如种族/民族移民妇女，比非西班牙裔白人妇女更不可能接受宫颈癌筛查。获得这种护理的障碍包括医疗保险、费用、知识、态度、卫生知识以及文化规范和做法。在这些群体中增加筛查的最有希望的方法是患者导航，可以将妇女与适当护理的来源联系起来。最近另一种很有希望的方法是使用人类乳头瘤病毒（HPV）自我采样。在这份手稿中，我们描述了我们国家癌症研究所赞助的研究，在移民少数民族妇女中测试这些方法。南佛罗里达减少癌症健康差异中心（SUCCESS）正在迈阿密戴德县的西班牙裔、海地裔和非洲裔美国妇女中进行一项三组随机试验。三个社区的社区卫生工作者在每个地点招募200名妇女（总共600名）。资格标准包括30-65岁的妇女，在过去3年内没有做过子宫颈抹片检查。在随机化之前，所有女性都接受了一次标准化的结构化访谈。随机分配到公共卫生外展的妇女，即第一组，接受符合文化特点的教育材料。第2组的妇女接受个体化的全面宫颈癌卫生健康中心教育课程，然后由患者指导在社区设施进行子宫颈抹片检查。第3组的妇女可以选择进行巴氏涂片检查或进行HPV自我取样。主要结果是在入组后6个月内通过巴氏涂片检查或HPV自我抽样完成筛查的自我报告。SUCCESS是首批在服务不足的少数民族妇女中测试HPV自我抽样作为筛查策略的试验之一。如果成功，HPV自我抽样可能是旨在减少宫颈癌差异的社区外展计划的重要选择。临床试验。gov # NCT02121548，注册于2014年4月21日。
In the United States certain minority groups, such as racial/ethnic immigrant women, are less likely than non-Hispanic White women to be screened for cervical cancer. Barriers to such care include health insurance, cost, knowledge, attitudes, health literacy, and cultural norms and practices. Among the most promising approaches to increase screening in these groups are patient navigators that can link women to sources of appropriate care. Another recent promising approach is using human papilloma virus (HPV) self-sampling. In this manuscript, we describe our National Cancer Institute-sponsored study testing such approaches among immigrant minority women. The South Florida Center for the Reduction of Cancer Health Disparities (SUCCESS) is conducting a three-arm randomized trial among Hispanic, Haitian, and African American women in Miami-Dade County. Community health workers (CHW) based in each of three communities are recruiting 200 women at each site (600 total). Eligibility criteria include women aged 30–65 years who have not had a Pap smear test in the last 3 years. Prior to randomization, all women undergo a standardized structured interview. Women randomized to public health outreach, Group 1, receive culturally tailored educational materials. Women in Group 2 receive an individualized comprehensive cervical cancer CHW-led education session followed by patient navigation to obtain the Pap smear test at community-based facilities. Women in Group 3 have the option of navigation to a Pap smear test or performing HPV self-sampling. The primary outcome is self-report of completed screening through a Pap smear test or HPV self-sampling within 6 months after enrollment. SUCCESS is one of the first trials testing HPV self-sampling as a screening strategy among underserved minority women. If successful, HPV self-sampling may be an important option in community outreach programs aimed at reducing disparities in cervical cancer. Clinical Trials.gov # NCT02121548, registered April 21, 2014.
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