Multiple guide stars optimization in conjugate adaptive optics for deep tissue imaging
Multiple guide stars optimization in conjugate adaptive optics for deep tissue imaging
复制标题
深层组织成像共轭自适应光学中的多导星优化
DOI:
10.1016/j.optcom.2019.124891
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发表时间:
2020-03
影响因子:
2.4
通讯作者:
Wei Gong
中科院分区:
文献类型:
--
作者:
Chenxue Wu;Jiajia Chen;Biwei Zhang;Yao Zheng;Xinpei Zhu;Ke Si;Wei Gong
Adaptive optics (AO) has been widely used in optical microscopy to recover high-resolution images in deep tissue. However, in conventional AO systems, the corrected field of view (FOV) of a single guide star is usually quite limited. Here we demonstrate a conjugate AO system based on automatic optimal multiple guide stars selection algorithm to achieve large effective corrected FOV with a small number of guide stars. For a random phase mask as the scattering medium, the effective correction coverage ratio can be increased to∼ 5.09 times than that in a conventional CAO system. For a mouse brain slice with 117 μ m thickness, the effective corrected FOV is larger than that of conventional CAO system by a factor of∼ 2.58. Therefore, our method shows potentials in aberration correction with large FOV for deep tissue imaging
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影响因子:
1.9
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通讯作者:
Bifano TG
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48
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通讯作者:
Yuste R
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Shroff H
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4.6
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48
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通讯作者:
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