Complete nucleotide sequence of the nucleoprotein gene from the human influenza strain A/PR/8/34 (HON1).
Complete nucleotide sequence of the nucleoprotein gene from the human influenza strain A/PR/8/34 (HON1).
复制标题
人流感病毒株 A/PR/8/34 (HON1) 核蛋白基因的完整核苷酸序列。
DOI：
10.1111/j.1432-1033.1981.tb05341.x
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
W. Fiers
中科院分区：
文献类型：
--
作者：
L. Rompuy;W. Jou;D. Huylebroeck;R. Devos;W. Fiers
在pBR 322中克隆dsDNA拷贝后，确定流感A/PR/8/34核蛋白基因的完整核苷酸序列。核蛋白基因全长1517个核苷酸，其中1446个核苷酸编码482个氨基酸。计算的氨基酸组成是在良好的协议与那些公布的甲型流感病毒核蛋白基因。核蛋白的氨基酸序列含有碱性氨基酸簇和脯氨酸，这是与其他核酸相关蛋白如塞姆利基森林病毒核衣壳蛋白、多瘤病毒和猿猴病毒40的VP 1蛋白以及B型肝炎病毒的核心抗原共有的性质。所描述的核蛋白结构使流感A/PR/8/34的测序基因的数量达到8个基因中的5个。
The complete nucleotide sequence of the influenza A/PR/8/34 nucleoprotein gene was determined after cloning for dsDNA copy in pBR322. The nucleoprotein gene is 1517 nucleotides long of which 1446 nucleotides code for 482 amino acids. The calculated amino acid composition is in good agreement with those published for influenza A nucleoprotein genes. The amino acid sequence of the nucleoprotein contains clusters of basic amino acids and proline, a property shared with other nucleic-acid-associated proteins like Semliki forest virus nucleocapsid protein, VP1 protein of polyoma virus and Simian virus 40, and the core antigen of hepatitis B virus. The described nucleoprotein structure brings the number of sequenced genes of influenza A/PR/8/34 to five out of eight genes.
影响因子：
14.9
作者：
M. Baez;R. Taussig;J. Zazra;J. F. Young;P. Palese;A. Reisfeld;A. Skalka
通讯作者：
M. Baez;R. Taussig;J. Zazra;J. F. Young;P. Palese;A. Reisfeld;A. Skalka