A Computational Fluid Mechanical Study on the Effects of Opening and Closing of the Mitral Orifice on a Transmitral Flow Velocity Profile and an Early Diastolic Intraventricular Flow
A Computational Fluid Mechanical Study on the Effects of Opening and Closing of the Mitral Orifice on a Transmitral Flow Velocity Profile and an Early Diastolic Intraventricular Flow
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二尖瓣口打开和关闭对经二尖瓣血流速度分布和舒张早期心室内血流影响的计算流体力学研究
DOI：
10.1299/jsmec.45.913
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
T. Karino
中科院分区：
文献类型：
--
作者：
Masanori Nakamura;S. Wada;T. Mikami;A. Kitabatake;T. Karino
计算流体动力学研究心室内血流在早期二尖瓣进行检查的二尖瓣口的大小的变化，由于开放和关闭的二尖瓣对血流演变的影响在左心室早期二尖瓣。结果表明，二尖瓣口逐渐开放时，二尖瓣口中心处流速最大，二尖瓣口完全开放后流速仍保持不变。这种经二尖瓣血流导致形成从左心室前侧延伸到后侧的涡环。涡流环保持主流入流线性流向心室尖。这种流型在临床上获得的彩色M型多普勒超声心动图中产生细长形状的混叠区域。因此，人们认为，虽然二尖瓣口的打开和关闭发生的时间很短，但它们在表征早期二尖瓣期间的心室内血流方面起着重要作用。
A computational fluid dynamics study of intraventricular flow during early diastole is carried out to examine the effect of a change in the size of the mitral orifice due to opening and closing of the mitral valve on the flow evolution in the left ventricle during early diastole. It is found that a velocity profile of a transmitral flow with maximum velocity locating at the center of the mitral orifice is generated by gradual opening of the mitral orifice, and it remains even after the mitral orifice has fully opened. This transmitral flow causes the development of a vortex ring extending from the anterior to the posterior side of the left ventricle. The vortex ring keeps the main inflow to stream linearly toward the ventricular apex. Such a flow pattern produces an elongated shape of an aliasing area in a color M-mode Doppler echocardiogram obtained clinically. It is, therefore, considered that although opening and closing of the mitral orifice occur with a short period, they play an important role in characterizing intraventricular flow during early diastole.
影响因子：
9.1
作者：
Yellin,EL;Nikolic,S;Frater,RW
通讯作者：
Frater,RW
DOI：
10.1115/1.1286559
发表时间：
2000-08-01
影响因子：
1.7
作者：
Lemmon, JD;Yoganathan, AP
通讯作者：
Yoganathan, AP
DOI：
10.1115/1.429648
发表时间：
2000-04-01
影响因子：
1.7
作者：
Lemmon, JD;Yoganathan, AP
通讯作者：
Yoganathan, AP