Trends in breast biopsy pathology diagnoses among women undergoing mammography in the United States: a report from the Breast Cancer Surveillance Consortium.
Trends in breast biopsy pathology diagnoses among women undergoing mammography in the United States: a report from the Breast Cancer Surveillance Consortium.
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DOI：
10.1002/cncr.29199
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发表时间：
2015-05-01
期刊：
影响因子：
6.2
通讯作者：
Elmore, Joann G.
中科院分区：
文献类型：
--
作者：
Allison, Kimberly H.;Abraham, Linn A.;Weaver, Donald L.;Tosteson, Anna N. A.;Nelson, Heidi D.;Onega, Tracy;Geller, Berta M.;Kerlikowske, Karla;Carney, Patricia A.;Ichikawa, Laura E.;Buist, Diana S. M.;Elmore, Joann G.
关键词：
乳房x光检查后乳腺活检病理诊断的最新数据可以告知患者、临床医生和研究人员重要的人口趋势。乳腺癌监测协会的数据显示，1996年至2008年间，4020140张乳房x光照片与76567个病理标本有关。按时间和危险因素（患者年龄、乳腺密度和乳腺癌家族史）检查活检诊断趋势，以进行筛查和诊断性乳房x光检查（针对乳房症状或短间隔随访）。在所有的乳房x光检查中，88.5%是筛查，11.5%是诊断；1.2%的筛查和6.8%的诊断性乳房x光检查随后进行了活组织检查。在筛查性乳房x光检查后，活检的频率随着时间的推移保持稳定，但在诊断性乳房x光检查后增加。对于筛查后获得的活检，40-49岁和60-69岁的女性浸润性癌的频率随着时间的推移而增加，40-69岁的DCIS增加，而良性诊断在所有年龄段都有所减少。诊断性乳房x光检查后未发现病理诊断的趋势。相对于非致密乳腺组织，致密乳腺组织与高危病变和DCIS相关。乳腺癌家族史与DCIS和浸润性癌相关。虽然乳腺活检筛查后的乳腺活检频率没有随着时间的推移而改变，但诊断为DCIS和浸润性癌症的活检比例有所增加。在乳房x光检查后的活组织检查中，乳房致密或有乳腺癌家族史的女性更有可能患高风险病变或浸润性癌症。这些发现与乳腺癌筛查和诊断实践有关。
Current data on the pathologic diagnoses of breast biopsy after mammography can inform patients, clinicians, and researchers about important population trends. Breast Cancer Surveillance Consortium data on 4,020,140 mammograms between 1996 and 2008 were linked to 76,567 pathology specimens. Trends in diagnoses in biopsies by time and risk factors (patient age, breast density, and family history of breast cancer) were examined for screening and diagnostic mammography (performed for a breast symptom or short interval follow-up). Of the total mammograms, 88.5% were screening and 11.5% diagnostic; 1.2% of screening and 6.8% of diagnostic mammograms were followed by biopsies. The frequency of biopsies over time was stable after screening mammograms, but increased after diagnostic mammograms. For biopsies obtained after screening, frequencies of invasive carcinoma increased over time for women aged 40–49 and 60–69, DCIS increased for 40–69, while benign diagnoses decreased for all ages. No trends in pathology diagnoses were found following diagnostic mammograms. Dense breast tissue was associated with high-risk lesions and DCIS relative to non-dense breast tissue. Family history of breast cancer was associated with DCIS and invasive cancer. While the frequency of breast biopsy after screening mammography has not changed over time, the percentages of biopsies with DCIS and invasive cancer diagnoses have increased. Among biopsies following mammography, women with dense breasts or family history of breast cancer were more likely to have high-risk lesions or invasive cancer. These findings are relevant to breast cancer screening and diagnostic practices.
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影响因子：
39.2
作者：
Nelson HD;Zakher B;Cantor A;Fu R;Griffin J;O'Meara ES;Buist DS;Kerlikowske K;van Ravesteyn NT;Trentham-Dietz A;Mandelblatt JS;Miglioretti DL
通讯作者：
Miglioretti DL
影响因子：
39.2
作者：
Hubbard RA;Kerlikowske K;Flowers CI;Yankaskas BC;Zhu W;Miglioretti DL
通讯作者：
Miglioretti DL
影响因子：
158.5
作者：
Pisano, ED;Gatsonis, C;Rebner, M
通讯作者：
Rebner, M
DOI：
10.1186/bcr3080
发表时间：
2011
期刊：
Breast cancer research : BCR
影响因子：
--
作者：
Lehtimäki T;Lundin M;Linder N;Sihto H;Holli K;Turpeenniemi-Hujanen T;Kataja V;Isola J;Joensuu H;Lundin J
通讯作者：
Lundin J
影响因子：
39.2
作者：
Kerlikowske K;Hubbard RA;Miglioretti DL;Geller BM;Yankaskas BC;Lehman CD;Taplin SH;Sickles EA;Breast Cancer Surveillance Consortium
通讯作者：
Breast Cancer Surveillance Consortium