Mitochondrial DNA control region sequences may differentiate Yanbian Koreans in China from other Asian populations
Mitochondrial DNA control region sequences may differentiate Yanbian Koreans in China from other Asian populations
复制标题
线粒体DNA控制区序列可能将中国延边朝鲜族与其他亚洲人群区分开来
DOI：
10.1080/03014460.2017.1288760
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发表时间：
2017-02
影响因子：
1.7
通讯作者：
Wang Bao-jie
中科院分区：
文献类型：
--
作者：
Li Xiao-na;Zheng Ji-long;Yao Jun;Dong Yue;Shi Zhang-sen;Wang Bao-jie
摘要背景：线粒体DNA（mtDNA）序列多态性在法医学和人类遗传学中具有重要的应用价值。目的：本研究调查了中华人民共和国延边朝鲜族自治州295名无关个体的线粒体DNA控制区序列。对象和方法：从染血滤纸中提取DNA。扩增mtDNA控制区的高变区（HVI和HVII）并测序。将所得序列与修订的剑桥参考序列（rCRS）进行比对和比较。结果：共确认182个变异。种群间比较表明，延边朝鲜族与其他纳入种群间存在显著差异。结论：这些结果为人类遗传学研究和法医学检验提供了有用的数据，并证明延边朝鲜族是一个近亲通婚的东北亚群体。
Abstract Background: Sequence polymorphisms of mitochondrial DNA (mtDNA) are valuable in forensic medicine and anthropological genetics. Aim: This study investigated the mtDNA control region sequences in 295 unrelated individuals living in the Yanbian Korean Autonomous Prefecture in the People’s Republic of China. Subjects and methods: DNA was extracted from blood stained filter papers. Hypervariable regions of the mtDNA control region (HVI and HVII) were amplified and sequenced. The resulting sequences were aligned and compared with the revised Cambridge reference sequence (rCRS). Results: A total of 182 variations were confirmed. Population comparison showed the significant difference between Yanbian Korean and other included populations. Conclusion: These results provide useful data for human genetic studies and forensic examinations and demonstrate that the Yanbian Korean population is an endogamous Northeast Asian group.
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影响因子：
2.7
作者：
WALSH, PS;METZGER, DA;HIGUCHI, R
通讯作者：
HIGUCHI, R
中国毛南族人群线粒体DNA控制区序列的调查
影响因子：
--
作者：
Meng Jing-Hua;Yao Jun;Xing Jia-Xin;Xuan Jin-Feng;Wang Bao-Jie;Ding Mei
通讯作者：
Ding Mei
影响因子：
14.9
作者：
Weissensteiner H;Pacher D;Kloss-Brandstätter A;Forer L;Specht G;Bandelt HJ;Kronenberg F;Salas A;Schönherr S
通讯作者：
Schönherr S
DOI：
--
发表时间：
1997-07
期刊：
Development and Society
影响因子：
--
作者：
T. Kwon
通讯作者：
T. Kwon
影响因子：
2.1
作者：
Aboukhalid, Rachid;Sturk-Andreaggi, Kimberly;Amzazi, Saaid
通讯作者：
Amzazi, Saaid