Induced regeneration--the progress and promise of direct reprogramming for heart repair.

Induced regeneration--the progress and promise of direct reprogramming for heart repair.
复制标题

DOI:
10.1038/nm.3225
复制
发表时间:
2013-07
期刊:
影响因子:
82.9
通讯作者:
--
中科院分区:
医学1区
文献类型:
--
作者:

文献摘要

参考文献

被引文献

相似文献

心脏组织的再生具有改变心血管医学的潜力。干细胞生物学和直接重编程或转分化的最新进展已经产生了强大的新工具来推进这一目标。在这篇综述中,我们研究了在体外产生新的心肌细胞的关键发展,以及在体内心脏组织重编程方面取得的令人兴奋的进展。我们还解决挑战该领域的争议和障碍。
Regeneration of cardiac tissue has the potential to transform cardiovascular medicine. Recent advances in stem cell biology and direct reprogramming, or transdifferentiation, have produced powerful new tools to advance this goal. In this Review we examine key developments in the generation of new cardiomyocytes in vitro as well as the exciting progress that has been made toward in vivo reprogramming of cardiac tissue. We also address controversies and hurdles that challenge the field.
DOI: 10.1016/j.stem.2011.12.013
发表时间: 2012-01-06
期刊: CELL STEM CELL
影响因子: 23.9
作者:
Burridge, Paul W.;Keller, Gordon;Gold, Joseph D.;Wu, Joseph C.
通讯作者: Wu, Joseph C.
DOI: 10.2741/4002
发表时间: 2012-01-01
影响因子: 3.1
作者:
Chiu, Loraine L. Y.;Iyer, Rohin K.;Radisic, Milica
通讯作者: Radisic, Milica
DOI: 10.1073/pnas.0711961105
发表时间: 2008-04-22
影响因子: 11.1
作者:
Feng, Ru;Desbordes, Sabrina C.;Graf, Thomas
通讯作者: Graf, Thomas
DOI: 10.1016/j.stem.2008.06.009
发表时间: 2008-07-01
期刊: CELL STEM CELL
影响因子: 23.9
作者:
Bondue, Antoine;Lapouge, Gaelle;Blanpain, Cedric
通讯作者: Blanpain, Cedric
DOI: 10.1128/mcb.14.6.4269
发表时间: 1994-06-01
影响因子: 5.3
作者:
EVANS, SM;TAI, LJ;CHIEN, KR
通讯作者: CHIEN, KR