Refinement of protein structure against non-redundant carbonyl 13C NMR relaxation.
Refinement of protein structure against non-redundant carbonyl 13C NMR relaxation.
复制标题
针对非冗余羰基 13C NMR 弛豫精修蛋白质结构。
DOI：
10.1007/s10858-007-9165-7
复制
发表时间：
2007
影响因子：
2.7
通讯作者：
Chang,Shou-Lin
中科院分区：
文献类型：
--
作者：
Tjandra,Nico;Suzuki,Motoshi;Chang,Shou-Lin
Carbonyl13C′ relaxation is dominated by the contribution from the13C′ chemical shift anisotropy (CSA). The relaxation rates provide useful and non-redundant structural information in addition to dynamic parameters. It is straightforward to acquire, and offers complimentary structural information to the15N relaxation data. Furthermore, the non-axial nature of the13C′ CSA tensor results in a T1/T2value that depends on an additional angular variable even when the diffusion tensor of the protein molecule is axially symmetric. This dependence on an extra degree of freedom provides new geometrical information that is not available from the NH dipolar relaxation. A protocol that incorporates such structural restraints into NMR structure calculation was developed within the program Xplor-NIH. Its application was illustrated with the yeast Fis1 NMR structure. Refinement against the13C′ T1/T2improved the overall quality of the structure, as evaluated by cross-validation against the residual dipolar coupling as well as the15N relaxation data. In addition, possible variations of the CSA tensor were addressed.
登录
查看更多内容
氟碳多元醇人造血液代用品。
DOI：
10.1056/nejm197311152892008
发表时间：
1973
期刊：
The New England journal of medicine
影响因子：
--
作者：
R. Geyer
通讯作者：
R. Geyer
全氟丙烷气体治疗增殖性玻璃体视网膜病变。
影响因子：
4.2
作者：
Stanley Chang;D. J. Coleman;Harvey Lincoff;Lloyd M. Wilcox;James M. Maisel;Roberta Braunstein
通讯作者：
Roberta Braunstein
全氟醚液体作为长期玻璃替代品：实验研究
DOI：
10.1097/00006982-198400440-00010
发表时间：
1984
期刊：
Retina
影响因子：
--
作者：
K. Miyamoto;M. Refojo;F. Tolentino;G. Fournier;D. Albert
通讯作者：
D. Albert
治疗性超声治疗视网膜脱离：临床观察以及光电子显微镜
DOI：
10.1097/00006982-198500520-00010
发表时间：
1985
期刊：
Retina
影响因子：
--
作者：
L. R. Rosecan;T. Iwamoto;A. Rosado;F. Lizzi;D. Coleman
通讯作者：
D. Coleman
玻璃体手术中的全氟化碳气体。
影响因子：
13.7
作者：
Stanley Chang;H. Lincoff;D. J. Coleman;W. Fuchs;M. Farber
通讯作者：
M. Farber